维拉帕米联合利多卡因对家兔的表面麻醉作用  

Surface anesthetic effects of verapamil hydrochloride combined with lidocaine hydrochloride on rabbits

作　　者：刘亮[1] 丁敏敏[1] 刘毅[1] 朱江[1] 戴体俊[2] 

机构地区：[1]徐州医学院麻醉学院,2005级6班江苏徐州221004 [2]徐州医学院麻醉药理学教研室

出　　处：《徐州医学院学报》2009年第1期14-15,共2页Acta Academiae Medicinae Xuzhou

摘　　要：目的观察维拉帕米联合利多卡因对兔表面麻醉作用的影响。方法选取12只家兔,用眨眼反射实验分别观察生理盐水、利多卡因联用(左眼)或维拉帕米、利多卡因联用(右眼)对家兔表面麻醉作用的影响。结果右眼的眨眼次数明显少于左眼(P<0.01)。结论维拉帕米可增强利多卡因的表面麻醉作用。Objective To observe the surface anesthetic effect of verapamil hydrochloride combined with lidocaine hydrochloride on rabbits. Methods 12 rabbits were used in the blink reflex experiment to observe the surface anesthetic effect of physiological saline combined with lidocaine hydrochloride （ left eye）, and verapamil hydrochloriden combined with lidocaine hydrochloride （right eye） on rabbits respectively. Results Blink times of the right eye are fewer than those of the left eye （ P 〈 0.01 ）. Conclusion Verapamil hydrochloride can enhance the surface anesthetic effect of lidocaine hydrochloride.

关 键 词：维拉帕米 利多卡因 表面麻醉 眨眼反射 家兔 

分 类 号：R614[医药卫生—麻醉学]