后颅窝开颅术后无菌性脑膜炎的临床分析  

Clinical analysis of aseptic meningitis after the posterior fossa craniotomy

作　　者：崔刚[1] 吕健[1] 杨庆余[1] 屈建强[1] 

机构地区：[1]西安交通大学医学院第二附属医院神经外科,西安710004

出　　处：《临床神经外科杂志》2008年第4期189-191,共3页Journal of Clinical Neurosurgery

摘　　要：目的探讨后颅窝开颅术后无菌性脑膜炎的诊断和治疗。方法回顾性分析16例后颅窝开颅术后无菌性脑膜炎患者的临床特点和治疗方式。结果16例患者均有发热,体温37.5～40.1℃,白细胞计数(45～110)×106/L,脑脊液糖定量(2.2～3.9)mmol/L,细菌培养阴性;所有患者均接受地塞米松静脉注射和鞘内注射治疗;6例间断腰穿,10例腰穿置管持续引流;16例患者均治愈,其中14例院内治愈,2例自动出院,4月内自愈。结论术后3d开始发热,脑脊液白细胞数增高,糖定量正常和细菌培养阴性可以诊断为无菌性脑膜炎;激素治疗和脑脊液引流是治疗无菌性脑膜炎的主要手段。Objective To explore the diagnosis and treatment of aseptic meningitis after posterior fossa craniotomy. Method Retrospective analysis is made of the clinical characters and the treatment of 16 cases who suffered aseptic meningitis after the posterior fossa craniotomy. Results All the patients got fever, ranging from 37. 5℃ to 40. 1℃. Leukocyte count was （45 - 110） × 10^6/L, CSF glucose concentration （2.2 - 3.9） mmol/L, bacterial culture is negative. All the cases were treated with dexamethasone injection, in whom 6 were treated with intermittent intrathecal injection, 10 were undertaken lumber catheter drainage, 16 cases were cured, of whom 14 were cured in hospital and 2 discharged and recovered without medical treatment within 4 months. Conclusions The patients got feverin 3 days after the operations. The leukocyte count in CSF increased, glucose concentration was normal, and bacterial culture was negative, by which the patients were diagnosed aseptic meningitis. The steroids therapy and cerebrospinal fluid drainage are the main therapeutic methods.

关 键 词：后颅窝 开颅 无菌性脑膜炎 

分 类 号：R512.39[医药卫生—内科学]