应用M-型彩色多普勒测量舒张早期左室内血流传播速度——评价左室舒张功能的新指标  

Left Ventricular Filling Flow Propagation Velocity Assessed by Color M mode Doppler:A New Approach for Evaluation of Diastolic Function

作　　者：陈宇翔[1] 钱蕴秋[1] 张俊[1] 吴琳[1] 周晓东[1] 

机构地区：[1]西安市第四军医大学附属西京医院超声科

出　　处：《中国超声医学杂志》1998年第5期50-52,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：研究表明应用Ｍ型彩色多普勒测量的左室内血流传播速度与左室弛缓有关。为研究该方法的临床应用价值，本研究应用Ｍ型彩色多普勒测量了９５例正常人，３２例高血压，３０例冠心病，１０例扩张型心肌病和７例肥厚型心肌病患者的左室内舒张早期血流传播速度。同时用脉冲多普勒测量了二尖瓣口的血流速度频谱。结果显示：正常人心室内血流传播速度分别是６３．３±１０．２ｃｍ／ｓ（＜２０岁）、６２．６±１１．３ｃｍ／ｓ（２０～４０岁）、５９．４±１１．４ｃｍ／ｓ（４０岁），各种心脏病的心室内血流传播速度，不论是Ｅ／Ａ＞１还是Ｅ／Ａ＜１，均明显低于正常人的最低值（Ｐ值均小于０．０１）。结果表明：应用Ｍ型彩色多普勒测量的左室内血流传播速度能够无创、简便。Color M mode Doppler echocardiography has been suggested as a new noninvasive technique for assessing left ventricular diastolic function.To evaluate the clinical features,the velocity of left ventricular filling.To evaluate the clinical features,the velocity of left ventricular filling flow propagation were messured as the slope of the flow wave front in 95 normal subjects and 79 patients with four different diseases known to alter diastolic function [dilated cardiomyopathy(n=10),coronary artery disease(n=30),hypertrophic cardiomyopathy(n=7),systemic hypertension(n=32)].In normal subjects,the velocity of flow propagation were 63 3±10 2cm/s(age<20),62 6±11 3cm/s(20<age<40),59 4±11 4cm/s(age>40),respectively,As compare with normal,the velocity of flow propagation in patients were much lower[hypertrophic cardiomyopathy,38 2±12 3 vs 59 4±11 4cm/s(P<0 01);systemic hypertension,44 6±8 3vs.59 4±11 4cm/s(p<0 01);dilated cardiomyopathy,31 7±9 2vs.59 4±11 4cm/s(p<0 01);coronary artery disease,39 4±10 2vs.59 4±11 4cm/s(P<0 01)],no matter E/A>1 or E/A<1.The results suggested the velocity of left ventricular filling flow propagation measured by M mode color Doppler can assess diastolic function noninvasively and reliably,and was free of pseudonormalization.This method may be useful for evaluating diastolic dysfunction.

关 键 词：心室 舒张功能 彩超 

分 类 号：R540.4[医药卫生—心血管疾病]