高功率毫米波辐照对小鼠皮肤组织拉曼光谱的影响  

Raman Spectra of Murine Skin Irradiated by High Power Millimeter Wave

作　　者：张杰[1] 韩黎军[1] 谢涛嵘[1] 齐红星[1] 陈树德[1] 乔登江[1] 

机构地区：[1]华东师范大学物理系精密光谱科学与技术国家重点实验室,上海200062

出　　处：《光谱学与光谱分析》2008年第12期2872-2875,共4页Spectroscopy and Spectral Analysis

基　　金：国家"863-803"项目资助

摘　　要：运用显微激光拉曼仪测定了正常小鼠离体皮肤0-300μm不同深度的拉曼光谱。实验还测定了8 mm辐照一定时间后小鼠受辐照皮肤组织的拉曼光谱。实验结果表明毫米波辐照后皮肤拉曼光谱峰位857,936,1658 cm^-1的相对强度随着辐照时间的增加而减少。这表明由于毫米波热效应皮肤组织中的胶原蛋白构象发生了改变甚至分解,从而进一步表明皮肤组织受到了不可恢复的损伤。An experimental study on Raman spectroscopy of normal murine skin and the skin irradiated by high power millimeter wave（HPMM） is presented.It is showed that the Raman spectra of normal skin mainly originate from collagen,and the characteristic peaks are 857,936 and 1 658 cm- 1.The result showed that after irradiation by HPMM,the relative intensity of the characteristic peaks at 857 and 936 cm^-1 of Raman spectra was decreased.This meant that the collagen was destroyed and even damaged.It was probably indicated that the skin tissue was damaged and could not be restored.The result also showed that the intensity of the characteristic peak at 1 658 cm^-1 of the skin tissue irradiated by millimeter wave with the duration of 20 s decreased. It was considered that the protein in the skin was destroyed.Those results were consistent with macroscopic observation results.

关 键 词：高功率毫米波 皮肤组织 拉曼光谱 

分 类 号：Q68[生物学—生物物理学]