白塞病合并急性白血病五例临床分析  

Clinical analysis of 6 Behcet＇s disease patients with leukemia

作　　者：李芳[1] 李小峰[1] 张莉芸[1] 许珂[1] 

机构地区：[1]山西医科大学第二医院风湿免疫科,太原030001

出　　处：《中华风湿病学杂志》2009年第1期39-41,共3页Chinese Journal of Rheumatology

摘　　要：目的研究白塞病（BD）合并急性白血病的临床特征，探讨两者间的关系。方法选取5例BD病合并急性白血病病例进行临床分析。结果5例患者临床表现按发生率多少分别为：口腔溃疡和发热（5例）、皮肤损害（3例）、外阴溃疡（3例）、眼炎（3例）、关节痛（4例）、肠道溃疡及消化道出血（1例）。本组患者在发生急性白血病前近期内都有不同程度的外周血象改变，并且有免疫抑制剂使用史。合并的白血病：急性粒细胞白血病3例，急性单核细胞白血病1例、浆细胞白血病1例。5例患者在1年内均死亡。结论从发病诱因、临床表现、药物使用等方面分析，BD与白血病之间存在有一定的相关性。Objective To study the clinical characteristics of Behcet＇s disease （BD） complicated with leukemia and analyze the relationshp between the two diseases. Methods Five cases in the medical literature were retrieved and their data were analyzed. Results The clinical characteristics were ： oral ulcersand fever （5 cases）, skin lesions （3 cases）, vulva ulcers （3 cases）, eye lesions （3 cases）, arthralgia （4 cases）, digestive tract ulcerations and hemorrhage （1 cases）. All cases coexisted with leukemia were shown to have various degrees of peripheral blood changes and history of immunosuppressive therapy. Among these, 3 cases were coexisted with acute granulocytic leukemia, 1 case with acute monoeytic leukemia, 1 case with plasma cell leukemia respectively. All patients died within one year. Conclusion Close relationship can be observed between BD and leukemia from the point of view of the provocating factors, clinical features and drug use.

关 键 词：白塞病 急性白血病 临床分析 贝赫切特综合征 

分 类 号：R686[医药卫生—骨科学]