四川绵阳部分人群甲、乙、丙和戊型肝炎病毒感染血清学调查  

Hepatitis viruses infection situation in Mianyang of the Sichuan province

作　　者：张丽萍[1] 杨平[1] 李凤华[1] 闫钰[1] 文鸣[1] 张玉蓉[1] 江永珍[2] 

机构地区：[1]四川科学城医院,绵阳621900 [2]中国疾病预防控制中心病毒病预防控制所

出　　处：《中华实验和临床病毒学杂志》2008年第6期449-451,共3页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的了解健康人群肝炎病毒感染现状。方法采用ELISA方法检测体检人群血清中抗甲（HAV-IgG）、乙（HBsAg和HBsAb）、丙（HCV-IgG）和戊型肝炎病毒抗体（HEV-IgG和IgM）。人群血清均收集于2007年。结果1352份人群血清肝炎病毒抗体阳性率，HAV-IgG为81．07％（1096／1352），HBsAg和HBsAb为5．4％（73／1352）和61．32％（829／1352），HCV-IgG为0．37％（5／1352），HEV-IgG为49．26％（666／1352）。不同年龄段的人群HAV-IgG阳性率，10～19岁组为38．21％，20～29岁组为83％，30～39岁组为88％，40岁以上各年龄组为95．03％-97．77％。HBsAg和HBsAb阳性率，各年龄组依次为5．65％和50．83％、10．0％和68．0％、5．20％和78．80％、5．97％和78．11％、6．50％和62．50％、1．12％和51．40％、4．96％和30．58％。HCV-IgG阳性总数5份，其中10～19岁组1份，阳性率占0．33％，30～39岁组2份，占0．80％，60～69岁1份占0．56％，≥70岁1份占0．83％。HEV-IgG阳性率，10～19岁为26．58％，20～29岁组为42．0％，30岁以上各年龄组阳性率为55．22％～61．0％。对HEV-IgG阳性者再检测HEV-IgM，总阳性率为10．06％（53／527），各年龄组均有阳性者。结论青少年HAV和HBsAb抗体低于人群总体水平，应及时加强免疫预防。人群HBsAg和HCV感染率与往年相比下降明显。HEV感染率随年龄增长而升高，特别是各年龄段均有新近感染者，应加强餐饮和公共卫生管理。Objective To investigate the seroprevalence of hepatitis viruses in Mianyang of the Sichuan province .Methods EIISA was used for detecting anti-HAV IgG,HBsAg/HBsAb,anti-HCV IgG and anti-HEV IgG of the serum samples. All sample were collected in Mianyang areas in 2007. Results 1352 samples were detected. The positive rates of anti-HAV, HBsAg/HBsAb, anti-HCV, and anti-HEV are 81.07% （ 1096/1352）, 5.40% （73/ 1352） and 61.32% （829/1352）, 0.37% （5/1352） and 49.26% （666/1352）, respectively. The positive rate at different age group, for anti-HAV was 38.21% of 10-19 years old, 83 % of 20-29 years old, 88% of 30-39 years old,95.03% of 40-49 years old,97% of 50-59 years old,97.77% of 60-69 years old,97.52% of/〉70 years old. For HBsAg/HBsAb were 5.65% or 50.83%, 10.0% or 68.0%,5.20% or 78.80% ,5.97% or 78.11%, 6.50 % or 62.50 %, 1.12 % or 51.40 %, 4.96 % or 30.58 % at the same age group, respectively, for anti-HCV, was 0.33% of 10-19 yaers old,0.80% of 30-39 years,0.56% of 60-69 years old,0.83% of t〉70 years old. For HEV-IgG was 26.58% of 10-19 years old,42.0%of 20-29 years old,55.22%-61.0% of 30-≥70 years old,for anti-HEV IgM, was 10.06% （53/527） in the positive samples of HEV-IgG. Conclusion The inoculation againt HAV and HBV is enhanced in the young population. HBsAg carrier and HCV infection is decreasing. The HEV infection is actually increasing.

关 键 词：肝炎病毒 抗体/肝炎 血清分型 

分 类 号：R51[医药卫生—内科学]