纳米银海丝纤维抗菌性能和细胞毒作用的研究  

Study on antibacterial properties and cytotoxicity of seacell fibers filled with silver nanoparticles

作　　者：徐水凌[1] 

机构地区：[1]嘉兴学院,浙江嘉兴314001

出　　处：《纺织学报》2009年第1期13-17,共5页Journal of Textile Research

基　　金：浙江省"新苗人才计划"项目(2007G60G219014)

摘　　要：为确定纳米银海丝纤维的抗菌性能和细胞毒性作用,进行纳米银海丝纤维对金黄色葡萄球菌和大肠埃希菌的定性、定量抗菌实验,采用MTT法进行了纳米银对正常人肝细胞(L-02)的细胞毒性实验以评价其使用安全性。结果显示:用0.2%以上的纳米银海丝纤维对金黄色葡萄球菌(AATCC25923)和大肠埃希菌(AATCC25922)作用4 h均产生了明显的抗菌作用,抑菌率大于75%;纳米银颗粒对正常人肝细胞(L-02细胞)作用72 h,细胞相对增殖率(RGR)均在90.0%以上,细胞毒性均为1级,属无细胞毒性,细胞相容性好。纳米银海丝纤维具有高效抗菌活性,并且使用安全。In order to determine the antibacterial properties and cytotoxicity of the silver nanoparticles-filled seacell fibers, the qualitative and quantitative inhibition trials of the silver nanoparticles-filld seacell fibers against Staphylococcus aureus and Escherichia coli are investigated. The cytotoxicity tests of the silver nanoparticles on the L-02 cell lines are conducted to evaluate the safty with MTr cytotoxity assay. The results showed that more than 75% bacteria are inactivated when Staphylococcus aureus （AATCC25923） and Escherichia coli （AATCC25922） are incubated with 0.2% silver nanoparticles-filled seacell fibers for 4 h. MTY cytotoxicity test showed that the cell relative growth rates are over 90.0 % and the cytotoxicity is about 1 degree （no MTY cytotoxity）. The silver nanoparticles-filled seacell fibers show high antibacterial properties and less cytotoxicityl and can be used as a new type of textile material.

关 键 词：纳米银 海丝纤维 抗菌作用 细胞毒作用 

分 类 号：TS101.92[轻工技术与工程—纺织工程]