浆膜腔积液中细胞核仁组成区相关蛋白的研究  

Study on Nucleolar Organizer Region-associated Proteins in the Serous Membrane Fluid

作　　者：吴广平 黄秀霞 张振华 姜蕴波 焦岩 马红[1,2,3] 

机构地区：[1]第一临床学院检验科 [2]辽宁省血栓病中西医结合医疗中心 [3]辽宁省职业病医院

出　　处：《中国医科大学学报》1998年第1期69-71,共3页Journal of China Medical University

摘　　要：目的：探讨核仁组成区相关蛋白（ＡｇＮＯＲ）颗粒在浆膜腔积液中的诊断价值。方法：应用ＡｇＮＯＲ染色技术对８０例浆膜腔积液进行了颗粒的计数及形态观察。结果：恶性肿瘤、核异质及良性病变３组颗粒均数有显著性差异（Ｐ＜０．０１），而且颗粒的分布及形态亦不相同。结论：ＡｇＮＯＲ染色对浆膜腔积液的良恶性病变鉴别及动态观察有重要价值。Objective: The purpose of this paper was to investigate the diagnostic value of AgNOR granules in serous membrane fluid. Methods: Staining technique was used in Nucleolar-Organizer-Region-associaged Proteins to observe the amount and the shape of granules in the serous membrane fluid from 80 patients. Results: A marked difference existed in the average granular number among three groups, i.e malignant tumors, dyskaryosis, and benign pathological changes (P<0.01). The distribution and shape of AgNOR's granules was also different. Conclusion: The staining of AgNOR was of great value in discriminating the benign from the malignant dropsy of serous cavity, and in dynamic observation.

关 键 词：浆膜腔积液 AGNOR染色 细胞诊断学 

分 类 号：R442.9[医药卫生—诊断学] R446.19[医药卫生—临床医学]