伴有系膜增殖的肾小球肾炎195例病理损伤分析  

PATHOLOGICAL STUDY OF 195 CASES OF GLOMERULONEPHRITIS WITH MESANGIAL PROLIFERATION

作　　者：周庚寅[1] 谭燕泉[1] 刘洪琪[1] 刘文君 许复郁[1] 周志强[1] 段德刚[1] 

机构地区：[1]山东医科大学病理学教研室

出　　处：《山东医科大学学报》1998年第2期96-99,共4页Acta Academiae Medicinae Shandong

基　　金：山东省卫生厅科研基金

摘　　要：用光镜、免疫荧光显微镜及电镜观察了伴有系膜增生肾小球肾炎１９５例的病理损伤。结果表明，系膜增殖的程度与肾小球节段性硬化、新月体形成、毛细血管丛与球囊壁粘连、肾小管萎缩及肾间质纤维化密切相关。系膜增生可合并电子致密物内皮下沉积及基底膜变薄、撕裂等改变。One hundred and ninety five cases of primary and secondary glomerulonephritis with mesangial proliferation were observed with light,electron and immunofluorescent microscopes on the basis of renal biopsy.The results revealed that mesangial proliferative glomerulonephritis was the most common type of glomerulonephritis with mesangial proliferation followed by IgA nephropathy and Schoenlein Henoch Syndrome.There was no relationship between variable mesangial proliferation and inmmunofluorescent demonstration.Mesangial proliferation was related to the focal sclerosis,crescent formation,glomerular capillary tufts adhesion to Bowman's capsule,tubular atrophy and interstitial fibrosis.There was no specific finding of mesangial proliferation in membranous nephropathy.Subendothelial deposit and attenuation,focal splitting and trabeculation of glomerular basement membrane were identified besides mesangial deposits.

关 键 词：肾小球肾炎 系膜细胞 荧光抗体技术 病理学 

分 类 号：R692.310.2[医药卫生—泌尿科学]