青春期多囊卵巢综合征患者临床特征分析  

Clinical features of polycystic ovary syndrome among adolescent patients

作　　者：李琳[1] 杨冬梓[1] 陈晓莉[1] 陈亚肖[1] 李予[1] 何英明[1] 黄宇宏[1] 

机构地区：[1]广州中山大学附属第二医院妇产科,510120

出　　处：《中国妇产科临床杂志》2009年第1期27-30,共4页Chinese Journal of Clinical Obstetrics and Gynecology

基　　金："十一五"国家科技支持计划项目(2007BA104B00课题号2007BA104B04);教育部高等学校博士学科点专项科研基金项目(20050558093);广东省医学科研基金项目(B2007053)资助

摘　　要：目的探讨青春期多囊卵巢综合征(PCOS)患者的临床特征。方法回顾性分析2003年1月～2006年5月我院收治的青春期PCOS患者58例的临床资料。结果青春期PCOS患者中,超重者占39.7%,肥胖者占31.0%,月经异常、痤疮、多毛和黑棘皮症发生率分别为87.9%、65.5%、56.9%和6.9%,痤疮和多毛评分明显增高(分别为1.60±1.36和2.16±1.98),胰岛素抵抗发生率为12.7%。青春中期组与晚期组各项指标比较,差异无显著性(P>0.05)。结论肥胖、高雄激素血症和胰岛素抵抗是青春期PCOS患者的主要临床特征,应作为青春期PCOS的高危因素在临床上引起重视。Objective To explore the clinical features of adolescent patients with polycystic ovary syndrome （PCOS）. Method A retrospective analysis on 58 adolescent PCOS patients from January 2003 to May 2006 was conducted. Results The prevalence of overweight and obesity in PCOS group were 39.7% and 31.0%, respectively. The prevalences of menstrual abnormality, acne, hirsutism and acanthosis nigricans were 87. 9%, 65.5%, 56. 9 % and 6.9%, respectively. The score of acne and hirsutism were both higher than control （1.60± 1.36 and 2.16 ± 1.98, respectively）. The prevalence of insulin resistance was 12.7% in PCOS patients. No difference was found between mid - stage and late - stage adolescent patients. Conclusion Obesity, hyperandrogenism and insulin resistance are the main clinical features of adolescent PCOS, which should be regarded as the high risk factors of adolescent PCOS.

关 键 词：多囊卵巢综合征 青春期 胰岛素抵抗 高雄激素血症 

分 类 号：R711.75[医药卫生—妇产科学]