氨茶碱在心跳骤停心肺复苏中的临床研究  

Clinical study of aminophylline on cardiac arrest

作　　者：秦立红[1] 孙东兴[1] 董广苏 王广军[1] 

机构地区：[1]江苏省徐州市第三人民医院急诊科,221005

出　　处：《重庆医学》2009年第2期184-185,共2页Chongqing medicine

摘　　要：目的探讨氨茶碱在心脏骤停心肺复苏患者中的疗效。方法116例心脏骤停患者随机分为两组:氨茶碱组(n=58)心肺复苏时给予氨茶碱和肾上腺素联合用药,对照组(n=58)心肺复苏时单用肾上腺素,其他复苏用药两组相同,比较两组患者的心电活动和自主循环恢复情况及存活出院率。结果氨茶碱组恢复心电活动44例(75.86%),与对照组30例(51.72%)比较,差异有统计学意义(P<0.01);氨茶碱组恢复自主循环41例(70.69%),与对照组26例(44.83%)比较,差异有统计学意义(P<0.01);氨茶碱组存活出院6例(10.34%),与对照组5例(8.62%)比较,差异无统计学意义(P>0.05)。结论氨茶碱作为心脏骤停患者的辅助用药可促进心电活动和自主循环的恢复,但对预后无改善。Objectives To study the clinical effect of aminophylline on the treatment of cardiac arrest. Methods One hundred and sixteen cardiac arrest patients were randomly divided into two groups：the aminophyllinc group （58 cases） and the control group （58 cases）. The patients in the aminophylline group were treated with epinephrine and aminophylline,while the patients in the control group only with epinephrine. Cardiac electrical activity, spontaneous circulation and the rate of survival to hospital discharge were examined. Results Forty four cases （75. 86%） in the aminophylline group and 30 cases （512 72%） in the control group recovered cardiac electrical activity （P〈0.01）. Forty one cases （70.69 % ） in the aminophylline group recovered spontaneous circulation compared with 26 cases （44.83%） in the control group （P〈0.01）. Six cases （10.34%） in the aminophylline group and 5 cases （8.62%） in the control group survived to hospital discharge （P〉0.05）. Conclusion Aminophylline can promote the recovery of electrical activity and spontaneous circulation as the assistant drugs of cardiac arrest. However, aminophylline has no effect on the survival rate.

关 键 词：心脏骤停 氨茶碱 肾上腺素 

分 类 号：R541.78[医药卫生—心血管疾病]