踝臂指数评价2型糖尿病合并外周动脉疾病的价值  

Evaluation of ankle brachial index on type 2 diabetes patients with peripheral artery disease

作　　者：胡映玉[1] 路文盛[1] 颜晓东[1] 黄忠[1] 

机构地区：[1]广西壮族自治区人民医院内分泌代谢科,广西南宁530021

出　　处：《海南医学》2009年第1期20-22,共3页Hainan Medical Journal

摘　　要：目的观察2型糖尿病患者合并外周动脉疾病(PAD)的发病情况,探讨踝臂指数在临床上的应用价值。方法选取在住院的T2DM患者320例,收集相关临床资料并检测相关生化指标。采用多普勒血流探测仪专人测定糖尿病患者的足背动脉、胫后动脉与肱动脉的比值(踝臂指数),使用SPSS13.0统计软件进行数据分析和处理。结果2型糖尿病合并PAD的患者为92例,总的发病率为28.75%。2型糖尿病合并PAD组患者的血压、糖化血红蛋白(HbAlc)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、餐后2hC肽(P2h-CP)、血尿酸(UA)明显高于与2型糖尿病非PAD组(P<0.05)。PAD与年龄、血压、血尿酸有相关性(P<0.05)。结论增龄、高血糖、高血压、高低密度脂蛋白、高总胆固醇、高甘油三酯、高C肽水平及高尿酸是下肢动脉病变的危险因素;踝臂指数测定可作为早期诊断PAD的首选和常规检查手段。Objective To observe the incidence of the peripheral artery disease（PAD） in type 2 diabetes patients and to explore the clinical value of ankle brachial index. Methods A total of 320 cases were recruited from the department of endocrinology in our study. Collected clinical data to measure biochemical indicators. The data were analyzed by SPSS13. 0 software. Results The results revealed that there were 92 type 2 diabetes patients with PAD. The overall disease incidence is 28. 75%. Blood pressure, HbAlc, total cholesterol （ TC ）, triglycerides （ TG）, low - density lipoprotein（LDL）, postprandial two hours of C -peptide （P2h -CP） and serum uric acid （UA） in type 2 diabetes with PAD group are significantly higher than the non - PAD group （ P 〈 0. 05）. They are relevant with age, blood pressure, and blood uric acid（P 〈0. 05）. Conclusion Age, high blood glonse, high blood pressure, high LDL, high total cholesterol, high triglycerides, high C - peptide levels and high uric acid are risk factors of peripheral arterial disease. Ankle - brachial index is the first choice for the early diagnosis of PAD and conventional means of inspection.

关 键 词：2型糖尿病 踝臂指数 外周动脉疾病 

分 类 号：R587.2[医药卫生—内分泌]