氯雷他定、咪唑斯汀治疗慢性荨麻疹的疗效比较  

Efficaey and safety of loratadine versus mizolastine on chronic urticaria

作　　者：邢燕[1] 邹宇[1] 唐清体[1] 

机构地区：[1]成都铁路中心医院皮肤性病科,四川成都610081

出　　处：《四川医学》2009年第1期67-68,共2页Sichuan Medical Journal

摘　　要：目的了解氯雷他定、咪唑斯汀两种药物治疗慢性荨麻疹的疗效及不良反应。方法氯雷他定(开瑞坦)10mg/次,1次/d,与咪唑斯汀(皿治林)10mg/次,1次/d连续4周进行比较。结果两种药物对慢性荨麻疹的疗效分别为85.4%、83.3%,两组疗效比较差异无统计学意义,但开瑞坦不良反应相对较少、较轻。结论两种药物治疗慢性荨麻疹均有效,但氯雷他定不良反应轻、少。Objective To observe the efficacy and safety of lomtadine and mizolastine on chronic urticaria.Methods Patients were treated with loratadine（ Clarityne）lOmg per day and mizolastine（ Mizollen） 10mg per day respectively for 4 weeks.Results The efficacy rate was 85.4% for loratadine and 83.3 % for mizolastine, with no statistically significant. However, Clarityne had less and lighter side effect. Conclusion Both Ioratadine and mizolastine are effective on chronic urticaria,and loratadine has less and lighter side effect.

关 键 词：慢性荨麻疹 氯雷他定 咪唑斯汀 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]