麻黄超微粉体与常规粉体的体外溶出研究  

Exoteric dissolution of ultra-micro and traditional powder of herba ephedrae

作　　者：邹龙[1] 周春湘[1] 桂卉[1] 蔡光先[1] 唐正平[1] 

机构地区：[1]湖南中医药大学,长沙410007

出　　处：《中南药学》2009年第1期7-9,共3页Central South Pharmacy

基　　金：湖南省科技计划重大专项计划编号(05NK1004)

摘　　要：目的对麻黄的超微粉体和常规粉体中麻黄碱的体外溶出进行考察。方法采用HPLC法测定麻黄超微粉体与常规粉体中麻黄碱的溶出量和溶出速度。结果麻黄超微粉体与常规粉体中麻黄碱溶出量具有显著性差异,超微粉体的溶出速度较常规粉体明显增加。结论麻黄超微粉体的溶出量和溶出速度均优于其常规粉体。Objective To investigate the exoteric dissolution of ephedrine from the ultra-micro and traditional powder of herba ephedrae. Methods HPLC techniques were used to detect the dissolution amount and the dissolution rate of ephedrine from ultra-micro and traditional powder of herba ephedrae. Results There was statistically significant difference between the two powder of herba ephedrae in dissolution amount, and the dissolution rate of ultra-micro powder of herba ephedrae was increased obviously. Conclusion The dissolution amount and dissolution rate of ultra-micro powder of herba ephedrae are higher than those of traditional powder.

关 键 词：麻黄 超微粉体 常规粉体 溶出度 麻黄碱 

分 类 号：R927.2[医药卫生—药学]