高敏C-反应蛋白与肥胖及非肥胖儿童相关指标关系的探讨  

Study on high sensitivity C-reactive protein in children with and without obesity

作　　者：全壮志 张华[1] 

机构地区：[1]湖南省益阳市中心医院检验科,413000

出　　处：《中国临床实用医学》2009年第1期29-31,共3页China Clinical Practical Medicine

摘　　要：目的了解高敏C-反应蛋白（hs-CRP）在肥胖及非肥胖儿童体内的水平，探讨高敏C-反应蛋白与体重指数（BMI）、临床及实验室相关指标的关系。方法设计两平行组，将114例非肥胖儿童作为对照组，131例肥胖儿童作为研究对象，测量高敏C-反应蛋白水平及相关指标。结果肥胖组高敏C-反应蛋白水平明显高于对照组（P〈0．001）。生化指标空腹血糖和三酰甘油在肥胖组和对照组中有统计学意义（P〈0．01）。高敏C-反应蛋白与BMI之间呈明显相关性（P〈0．05）。结论高敏C-反应蛋白与BMI呈明显正相关；大部分非肥胖儿童的高敏C-反应蛋白浓度不超过2mg／L。Objective To determine the levels of high sensitivity C-reactive protein（hs-CRP）in children with and without obesity and their correlation with body mass index（BMI） and clinical and laboratory variables. Methods Two parallel groups were designed：the overweight group （obesity group, n = 131 ）and the control group（n = 114）. HsCRP concentrations and other serum parameters were determined. Results The obesity group exhibited greater hsCRP concentrations than the control group （ P 〈 0. 001 ）. Fasting plasma glucose （ FPG）, triglyceride （TG）were found significantly increased in overweight group compared to control group （P 〈 0. 01 ）. There were relationships between hs-CRP and BMI （ P 〈 0. 05 ）. Conclusion The hs-CRP concentrations increased as BMI increased. The majority of individuals who were notoverweight exhibited hsCRP concentrations of less than 2 mg/L.

关 键 词：肥胖 体重指数 相关性 高敏C-反应蛋白 

分 类 号：R7[医药卫生—临床医学]