五种消毒剂对鲍曼不动杆菌杀菌效果的实验研究  

EXPERIMENTAL STUDY ON EFFICACY OF FIVE DISINFECTANTS IN KILLING Acinetobacter baumannii

作　　者：林辉[1] 郑剑[1] 金春光[1] 章丹阳[1] 杨元斌[1] 沈玄艺[1] 

机构地区：[1]宁波市疾病预防控制中心,宁波315010

出　　处：《中国消毒学杂志》2009年第1期15-17,共3页Chinese Journal of Disinfection

摘　　要：目的了解五种常用消毒剂对临床分离的鲍曼不动杆菌的杀灭效果,为实际使用提供参考依据。方法采用悬液定量杀菌试验进行了实验观察,并与消毒试验指标菌大肠杆菌标准株作平行比较。结果用含有效氯400mg/L的含氯消毒液作用3 min、200 mg/L苯扎溴铵消毒液作用5 min、2500 mg/L有效碘的聚维酮碘消毒液和三氯生乙醇消毒液作用1 min以及含体积分数50%的乙醇溶液作用1 min,对临床分离的鲍曼不动杆菌和大肠杆菌标准菌株的平均杀灭率均能达到100%。临床分离的鲍曼不动杆菌与大肠杆菌标准株对上述五种消毒剂抗力没有明显差异。结论在常规使用浓度时,五种常用消毒剂对鲍曼不动杆菌临床分离株都具有良好的杀灭效果。Objective To study the efficacy of 5common disinfectants in killing clinically isolated Acinetobacter baumannii in order to provide a reference for practical use of disinfectants. Methods Suspension quantitative germicidal test was used to carry out experimental observation and the results in killing Acinetobacter baumannii were compared with those in killing the standard strain ofE. coli. Results An average bactericidal rate of 100% was observed when clinically isolated Acinetobacter baumannii or standard strain of E. coli was treated as follows ： Shikang disinfectant containing 400 mg/L of available chlorine for 3 minutes, benzalkonium bromide containing 200 mg/L of available bromine for 5 minutes, povidone iondine solution containing available iodine 2500 mg/L for 1 min, Triclosan for 1 min and 50% （v/v） ethanol solution for 1 min. No significant difference in the resistance against the five disinfectants was found between the clinical isolates of Acinetobacter baumannii and standard strain of E. coli. Conclusions The five disinfectants at routine concentration show excellent efficacy in killing clinically isolated Acinetobacter baumannii.

关 键 词：含氯消毒剂 聚维酮碘 乙醇 苯扎溴铵 鲍曼不动杆菌临床株 

分 类 号：R187.2[医药卫生—流行病学]