颈部血管滤泡淋巴组织增生病的诊断与治疗  

Diagnosis and treatment of Castleman disease in the neck

作　　者：邵姗[1] 谭静[1] 徐先发[2] 

机构地区：[1]首都医科大学附属北京朝阳医院耳鼻咽喉头颈外科,北京100020 [2]民航总医院北京大学民航临床医学院耳鼻咽喉头颈外科,北京100025

出　　处：《中国耳鼻咽喉头颈外科》2009年第1期27-30,共4页Chinese Archives of Otolaryngology-Head and Neck Surgery

摘　　要：目的探讨颈部血管滤泡淋巴组织增生病(Castleman disease,CD)的临床表现及诊治。方法回顾性分析我院收治的2例颈部CD患者的临床资料,分析其临床表现、临床及病理分型、影像学特征和治疗方案。结果2例颈部CD发病年龄分别为24岁和29岁,均以单发无痛性颈部肿块就诊,无其他特殊临床症状。临床分型符合局限型CD,病理分型均符合透明血管型CD。2例颈部肿块均完整手术切除,分别随访1年和半年无复发。结论颈部CD常为局限性病变,以单发无痛性肿块缓慢增大为主要表现,常无其他特殊临床症状。常见发病部位为颈部淋巴结,病理分型几乎全部为透明血管型。完整肿块切除是治疗颈部CD的最佳治疗方法。OBJECTIVE To investigate the clinical manifestation, diagnosis and treatment of Castleman disease （CD） in the neck. METHODS The data of 2 patients with pathological proved CD in the neck, who were seen in our hospital, were reviewed retrospectively in order to analyze their clinical manifestations, clinical and histological types, imaging characteristics and treatment. RESULTS The age of onset were 24 and 29 years respectively. Both of them only presented as a solitary, painless neck mass and met the criteria of localized CD, and also had histological evidence of the hyaline vascular variant. Complete surgical resection was the first treatment： Both of them were alive without evidence of recurrence for one year and half a year respectively. CONCLUSION CD in the neck often presents as localized lesion, which often presents as a progressive, painless, slowly growing lymph node enlargement that is generally asymptomatic. The locations most commonly are the cervical lymph nodes. CD in the neck is almost always the hyaline-vascular variant and complete surgical excision of the tumor is the best treatment.

关 键 词：巨淋巴结增生 颈 诊断 治疗 

分 类 号：R653[医药卫生—外科学] R733.102[医药卫生—临床医学]