潜艇艇员疗养前后抗氧化能力的变化  

Changs of oxidation and anti-oxidation capacity in submainers before and after convalesing

作　　者：贾妙兴[1] 付国顺[1] 陈孔斌[1] 

机构地区：[1]南京军区杭州疗养院海勤疗养区,浙江杭州310002

出　　处：《海军医学杂志》2008年第4期307-308,共2页Journal of Navy Medicine

摘　　要：目的:观察潜艇艇员疗养前后氧化与抗氧化能力的变化,探讨其疗养效果。方法:检测67名潜艇艇员疗养前后总的超氧化物歧化酶(T-SOD)、锰超氧化物歧化酶(MnSOD)、铜锌超氧化物歧化酶(CuZnSOD)、过氧化脂质(LPO)、一氧化氮(NO)的含量。结果:潜艇艇员疗养前后T-SOD,CuZnSOD的活力明显升高,差异有统计学意义(P<0.01,P<0.01);Mn-SOD无明显变化(P>0.05),LPO比疗养前明显下降(P<0.01),NO比疗养前明显上升(P<0.01)。结论:潜艇艇员疗养后机体抗氧化能力明显提高,身体得到了很好恢复,其中SOD、NO和LPO可作为疗养效果的评定指标。Objective： To investigate the changes of oxidation and anti - oxidation before and after convalesing in submainers and evaluate convalescent effect. Methods： The levels of some indexes in submariners before and after convalesing were measured, for example： total superoxide dismutase（T - SOD ）, manganese superoxide dismutase（MnSOD ）, cuprozinc - superoxide dismutase（CuZn- SOD）, lactoperoxidase（LPO）, nitrogen monoxidum（NO）. Results： Compared with before convalesing, the levels of T- SOD and CuZnSOD were significantly higher after convalesing （ P 〈 0.01, P 〈 0.01 ）. The level of LPO was decreased significantly （P 〈 0.01 ）. And there was no difference in M_nSOD （P 〉0.05）. Conclusions： After convalesing, the activeties of SOD and NO increased and that of LPO decreased in submariners. The results showed the body was more capable to anti - oxidation after convalesing. The three indexes can be used to evaluate convalescent effect.

关 键 词：潜艇艇员 超氧化物歧化酶 过氧化脂质 一氧化氮 

分 类 号：R82[医药卫生—临床医学]