黄连多糖抑菌活性初探  

The Antibacterial Effect of Coptis chinensis Polysaccharide

作　　者：姜延伟[1] 王懿萍[1] 吴玉娟[1] 洪鹏举[1] 许伦杰[1] 

机构地区：[1]西南交通大学药学院,四川峨眉山614202

出　　处：《时珍国医国药》2009年第1期48-49,共2页Lishizhen Medicine and Materia Medica Research

基　　金：四川省中医药管理局重点项目(No.2004A69)

摘　　要：目的探讨黄连多糖对大肠杆菌和金黄色葡萄球菌的抑制作用。方法用扩散法研究黄连多糖对大肠杆菌和金黄色葡萄球菌的抑制作用,并选用黄连水提液和盐酸小檗碱作为对照。结果黄连水提液和小檗碱对菌体均有抑菌效果,黄连水提液的抑菌效果尤为明显;黄连多糖没有抑菌作用。结论黄连多糖在体外条件下,不具有对大肠杆菌和金黄色葡萄球菌的抑制作用。Objective To research the in vitro growth inhibitory effect of Coptis chinensis polysaccharide, berberine and aqueous extract solution on Escherichia coli and staphylococcus aureus. Methods Dispersion method was used to observed the inhibitory effect of aqueous extract solution on Escherichia coli, staphylococcus aureus withberberine and Coptis chinensis polysaccharide as the compared samples. Results The aqueous extract solution and berberine had effect of growth inhibition on bacteria, and the an- tibacterial effect of aqueous extract solution was very obvious ; Coptis chinensis polysaccharide did not have the effect of growth in- hibition on bacteria. Conclusion Coptis chinensis polysaccharide may not have the effect of growth inhibition on Escherichia coli, stap hylococcus aureus.

关 键 词：黄连多糖 小檗碱 水提液 抑菌作用 

分 类 号：R285.5[医药卫生—中药学]