哺乳期女性乙型肝炎病毒携带者对婴儿的潜在传染性  

Female HBV carriers were potentially infectious to their infants in lactaion

作　　者：陆文英 

机构地区：[1]江苏省盐城市慈航医院,224001

出　　处：《实用医技杂志》2008年第34期14-15,共2页Journal of Practical Medical Techniques

摘　　要：目的探讨女性乙型肝炎病毒(HBV)携带者对婴儿的传染性,为指导哺乳提供辅助参考。方法采用酶联免疫吸附试验(ELISA)和荧光定量聚合酶链反应(PCR)检测80例女性HBV携带者、76名健康体检哺乳期妇女及其婴儿外周血中HBsAg和HBV DNA,携带者均排除产前感染;采用荧光定量PCR技术检测母乳中的HBVDNA,分析HBV携带者女性的婴儿和健康体检女性的婴儿HBV感染率的差异。结果在HBV女性携带者的婴儿外周血中HBV DNA阳性率为80.0%(64/80),HBsAg阳性率为78.8%(63/80);健康体检者女性的婴儿外周血中HBV DNA阳性率为2.6%(2/76),HBsAg未见阳性。结论哺乳期女性HBV携带者对婴儿可能具有传染性。Objective To investigate the infectiousness of the female HBV carriers.and to help doctors direct the female HBV careers to feed their infants. Methods Forty female HBV carriers and their infants was recruited, thirtyeight healthy females and their infants was studyed as control.Peripheral blood from all the fcmales arid infants was collected,milk from all tire females was also collected. HBsAg and HBV DNA in the peripheral blood were measured by ELISA and nuorescent quantitative PCR respectively, and HBV DNA was measured by nuorescent quantitative PCR. Results In the peripheral blood from the infants whose mothers were HBV carriers,the positive rate of HBV DNA was 80.0%（64/80）, and the positive rate of HBsAg was 78.8%（63/80）. But in the peripheral blood from tire infants whose mothers were healthy, the positive rate of HBV DNA was 2.6%（2/76）, and HBsAg was not detected. Conclusion The female HBV carriers in lactation were potentially infectious to their infants.

关 键 词：婴儿 女性HBV携带者 HBSAG HBV DNA 

分 类 号：R714.2[医药卫生—妇产科学] R512.62[医药卫生—临床医学]