平车前化学成分的研究  

Studies on Chemical Constituents of Plantago depressa Willd

作　　者：颜佩芳[1] 刘桂英[1] 赵士敏[1] 宋丽丽[1] 谭丽娜[1] 金永日[1] 李绪文[1] 

机构地区：[1]吉林大学化学学院,长春130012

出　　处：《中国药学杂志》2009年第1期19-21,共3页Chinese Pharmaceutical Journal

摘　　要：目的研究平车前(Plantago depressa Willd)的化学成分。方法采用体积分数95%乙醇提取,硅胶、ODS和Sephadex LH-20柱色谱法进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果分离得到7个化合物,分别为熊果酸(ursolic acid,1),大车前苷(plantamajoside,2),洋丁香酚苷(acteoside,3),车前草苷D(plantainoside D,4),大车前草苷(majoroside,5),10-羟基大车前草苷(10-hydroxymajoroside,6)和京尼平苷酸(geniposidic acid,7)。结论除了洋丁香酚苷之外,其余化合物均为首次从该植物中获得。OBJECTIVE To study the chemical constituents ofPlantago depressa Willd. METHODS The constituents were isolated and purified by column chromatography on silicagel, ODS and Sephadex LH-20 column. Compounds were identified by physicochemical and spectral data. RESULTS Seven compounds were isolated and identified as ursolic acid（1）, plantamajoside（2）, acteoside（3）, plantainoside D（4）, majoroside（5）, 10-hydroxymajoroside（6）, geniposidic acid（7）.CONCLUSION But for acteoside, all the compounds were isolated from Plantago depressa willd for the first time.

关 键 词：平车前 分离 鉴定 化学成分 

分 类 号：R248.1[医药卫生—中医临床基础]