鼻内镜外科干预对气道炎症转归的影响  

Influences of nasal endoscopic surgery on the outcomes of airway inflammatory diseases

作　　者：季俊峰[1] 王秋萍[1] 李泽卿[1] 江满杰[1] 王天友[1] 

机构地区：[1]南京军区南京总医院耳鼻喉-头颈外科,210002

出　　处：《实用医学杂志》2009年第3期418-420,共3页The Journal of Practical Medicine

基　　金：江苏省自然科学基金资助项目(编号:BK2006134)

摘　　要：目的:探讨鼻部炎症性疾病与气道炎症性疾病的关系,分析鼻内镜外科干预对气道炎症转归的影响。方法:对2003年10月至2007年12月随访观察至少3个月以上的824例经鼻内镜手术的患者资料进行临床分析。比较鼻部炎症性疾病和非炎症性疾病与下呼吸道炎症性疾病的相关性,分析鼻内镜外科干预对气道炎症转归的影响。结果:鼻部炎症性疾病(鼻息肉病、慢性鼻窦炎)伴有下呼吸道炎症性疾病者113例(包括支气管哮喘、支气管炎、支气管扩张)占16.5%,其中鼻息肉、哮喘、阿司匹林不耐受三联症者12例,鼻部非炎症性疾病伴有下呼吸道炎症者8例,占5.8%。两组对比差异有显著性(χ2=10.641,P<0.01)。鼻内镜术后下呼吸道炎症治愈27例,好转62例,病情无改变者24例,总改善率达到78.8%。其中支气管哮喘改善率69.6%,气管炎86.3%,支气管扩张100%。术中术后无一例出现因手术本身直接导致的病情加重。结论:需行鼻内镜手术的鼻息肉病、慢性鼻窦炎患者中有16.5%伴有程度不同的下呼吸道炎症性疾病;鼻内镜外科干预可明显改善甚至治愈伴发的下呼吸道炎症性疾病。Objective To explore the relationship between nasal inflammatory diseases and airway inflammatory diseases, and to analysis the influences of nasal endoscopic surgery on the outcomes of the latter. Methods The clinical data of 824 patients with a follow-up period of more than 3 months who had undergone endoscopic surgery from October 2003 to December 2007 were collected and analyzed retrospectively. The relationships between nasal inflammatory diseases or nasal non-inflammatory diseases and airway inflammatory diseases were compared. The influences of nasal endoscopic surgery on the outcomes of the＇latter were analyzed. Results 113 patients （16.5%） had nasal inflammatory diseases （including chronic sinusitis and nasal polyposis） eompanied with airway inflammatory diseases, including 12 cases with Widal triad. 8 patients （5.8%） had nasal non-inflammatory diseases companied with airway inflammatory diseases （X^2 = 10.641 ,P 〈 0.01 ）. In the 113 patients with nasal and airway inflammatory diseases, the total rate of improvement was 78.8%, 27 patients were cured, 62 were improved, and no change was observed in the other 24 cases. The improved rates were 69.6% in patients with asthma, 86.3% in bronchitis, 100% in tracheaectasy. No one aggravated directly due to the surgery. Conclusion There were 16.5% patients with chronic sinusitis and nasal polyposis who needed nasal endscopie surgery complicated with different state of airway inflammatory diseases, which could be improved or cured by nasal endoscopic surgery.

关 键 词：内窥镜检查 外科干预 气道炎症 

分 类 号：R765[医药卫生—耳鼻咽喉科] R56[医药卫生—临床医学]