数字化乳腺X线摄影检出BI-RADS 3～5级微钙化病变的动态增强MR研究  

Dynamic contrast-enhanced breast MRI for patients with BI-RADS 3-5 microcalcifications detected by digital mammography

作　　者：任阿红[1] 张晓鹏[1] 李洁[1] 孙应实[1] 唐磊[1] 曹崑[1] 欧阳涛[2] 王天峰[2] 陆爱萍[3] 

机构地区：[1]北京大学临床肿瘤学院、北京肿瘤医院暨北京市肿瘤防治研究所医学影像科,100036 [2]北京大学临床肿瘤学院、北京肿瘤医院乳腺中心,100036 [3]北京大学临床肿瘤学院、北京肿瘤医院病理科,100036

出　　处：《中国医学影像技术》2009年第1期89-92,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨DCE-MRI对数字化乳腺X线摄影检出BI-RADS3-5级微钙化病变的诊断价值。方法44例数字化乳腺X线摄影发现BI-RADS3-5级微钙化的患者于活检前完成双乳DCE-MR检查,以术后病理诊断为金标准,分析BI-RADS3～5级微钙化病变的DCE-MRI特点。结果病理证实良性微钙化病变13例,恶性微钙化病变31例。38.46%(5/13)良性单纯微钙化病变在DCE-MRI上无强化,93.33%(14/15)恶性微钙化伴肿块或局限性致密影病变在DCE-MRI上有明显强化,良恶性微钙化病变在DCE-MRI上早期增强率之间差异有显著统计学意义。DCE-MRI对微钙化病变诊断的敏感性和特异性分别为96.77%和92.31%。结论良恶性微钙化病变的DCE-MRI表现有明显差异,DCE-MRI有助于微钙化病变的定性诊断。Objective To investigate the value of dynamic contrast-enhanced breast MRI （DCE-MRI） for patients with BIRADS 3-5 microcalcifications detected on digital mammography. Methods Forty-four patients with mammographically detected BI-RADS category 3,4 or 5 microcalcifications were studied by DCE MRI before biopsies. Results Pathologic diagnoses revealed 31 malignant lesions and 13 benign ones, and 38.46% （5/13） of benign microcalcifications alone didn＇t enhance on DCE-MRI, 93.33% （14/15） of microealcifications associate with mass or density significantly enhanced on DCE-MRI were dural invasive carcinomas. Significant difference for initial enhancement was found between benign and malignant lesions. The sensitivity and specificity of DCE-MRI for BFRADS 3-5 microcalcifieations was 96. 77% and 92. 31%, respectively. Conclusion DCE MRI is helpful to differentiate malignant from benign lesions associated with microcalcifieations in breast.

关 键 词：乳腺肿瘤 数字化乳腺X线摄影 微钙化 磁共振成像 诊断 

分 类 号：R655.8[医药卫生—外科学] R445.2[医药卫生—临床医学]