定量组织速度成像评价犬急性左心缺血心肌非同步运动的实验研究  

Quantitative Tissue Velocity Imaging Evaluating on Ventricular Asynchrony of Canines in Acute Left Ventricular Myocardial Ischemia

作　　者：林萍[1] 刘长宏[2] 姜艳娜[1] 赵洋[1] 武俊[1] 夏稻子[1] 

机构地区：[1]大连医科大学附属二院超声科,辽宁省大连市116027 [2]大连医科大学附属二院胸外科,辽宁省大连市116027

出　　处：《中国超声医学杂志》2009年第2期105-107,共3页Chinese Journal of Ultrasound in Medicine

基　　金：大连市科技基金资助项目（No.2007J23H039）

摘　　要：目的探讨定量组织速度成像（QTVI）评价犬急性左心缺血时心肌非同步运动的价值。 方法健康犬18只，暴露心脏，于左冠状动脉前降支阻断前（对照组）、后（实验组）分别获取左心室12个节段的QTVI曲线，测量各位点ORS波起点至心肌收缩期峰值速度的时间（Ts），计算同一壁内3个节段Ts差值（Intra—△Ts）以及左心室12节段Ts的最大差值（Max—△Ts）。心室间的不同步指标测量ORS波起点到主动脉瓣血流频谱起点时间（Q—A），ORS波起点到肺动脉瓣血流频谱起点时间（Q—P）及其差值（Q—AP）。 结果实验组缺血节段Intra—△Ts和Max—△Ts较对照组明显延长（P〈0．01），而Q-A，Q-P及Q-AP较对照组无明显变化（P〉0．05）。 结论犬急性左心缺血时，左室内存在明显非同步运动，但心室间无明显不同步运动。Objective To discuss the value of Intra-and Interventricular asynchrony in acute left ventricular myocardial ischemia using quantitative tissue velocity imaging （QTVI） . Methods 18 canines were studied on QTVI, left anterior descending （LAD） artery was carefully dissected and occlusion . Before LAD occlusion, the canines were defined as the normal control group and after occlusion defined as the experiment group. The regional velocity profiles in 12 segments of left ventricle （LV） were obtained. The time from onset of QRS to peak velocity during systole （Ts） was measured. The maximal difference in Ts within the same wall （Intra-△Ts） and all 12 segments （Max- △Ts ）of the LV were calculated. The time from onset of QRS to beginning time of flow velocity spectra in aortic valve （Q-A） and pulmonary value （Q-P） and their differences （Q-AP） were measured. Results Intra-ATs, Max-△Ts were significantly prolonged compared with the control group. But Q-A . Q-P and Q-AP has no difference between two groups. Conclusions The intraventrieular asynchrony exists in canines with acute left ventricular ischemia, but has no difference between left and right ventricular.

关 键 词：定量组织速度成像 左心缺血 非同步运动 

分 类 号：R541.105[医药卫生—心血管疾病] R542.2[医药卫生—内科学]