南通市2000～2006年人群戊型肝炎病毒感染的血清流行病学调查  

A SEROEPIDEMIOLOGICAL SURVEY OF HEPATITIS E VIRUS INFECTION IN NANTONG CITY DURING 2000-2006

作　　者：严军英[1] 汤伟[2] 沈荣春[3] 汪晓莺[1] 

机构地区：[1]南通大学医学院微生物学与免疫学教研室,南通226001 [2]南通大学医学院传染病学教研室 [3]南通大学附属医院医学检验中心

出　　处：《现代预防医学》2009年第3期416-417,423,共3页Modern Preventive Medicine

摘　　要：[目的]了解2000～2006年南通市人群戊型肝炎病毒(hepatitis E virus,HEV)感染状况。[方法]对来自南通市的12537例受检者血清样本采用ELISA法检测抗HEV IgG和抗HEV IgM,分析该人群中血清HEV抗体阳性率的变化趋势。[结果]2000～2003年南通市人群HEV感染率从20.03%逐步下降到4.85%,2003～2006年HEV感染率维持在4.40%左右的较低水平;不同年龄组人群中,15岁以下未成年人HEV感染率仅为1.39%,显著低于25～64岁成年人(平均为8.17%,P≤0.005);男女两性感染率差异无统计学意义。[结论]2000～2006年南通市HEV感染率逐渐下降并维持于较低水平,HEV感染率存在年龄差异,男女感染率基本相同。[Objective] To explore the seroprevalence of hepatitis E virus （HEV） infection in the population of Nantong City during 2000-2006. [ Methods] The serum samples of 12 537 cases from Nantong City were detected for anti-HEV IgG and anti-HEV IgM antibodies with the method of EIJSA so as to calculate the seroprevalenee for HEV. [ Results] The sero- prevalence of HEV in crowds of Nantong City descended from 20.03% to 4.85% during 2000-2003, then it maintained a mean level of 4.40% during the years 2003-2006. Although no significance was observed between the male and the female, the preva- lence of the adult population aged 25-64 was significantly higher than that of the minor below 15 years old （8A7% vs 1.39%, P≤0.005）. [ Conclusion] During 2000-2006, the prevalence of HEV in Nantong City has gradually declined by 2003 and maintains a relatively low level. This study also indicates that the prevalence of HEV defers in age but not in gender.

关 键 词：戊型肝炎病毒 感染率 血清流行病学 

分 类 号：R512.6[医药卫生—内科学] R181.36[医药卫生—临床医学]