芙蓉膏外敷治疗软组织感染临床研究  

Clinical Study on Treatment of Soft-tissue Infection by the External Application of Furong Ointment

作　　者：于庆生[1] 王炜[1] 侯勇[1] 沈瑜[1] 汪晓明[1] 易为真[1] 潘晋方[1] 王汉明[1] 帅剑锋[1] 李华钢[1] 张琦[1] 张福忠[1] 

机构地区：[1]安徽中医学院第一附属医院普外科,安徽合肥230031

出　　处：《安徽中医学院学报》2009年第1期13-15,共3页Journal of Anhui Traditional Chinese Medical College

摘　　要：目的:观察芙蓉膏外敷治疗浅表软组织感染的临床疗效、毒性和不良反应。方法:340例浅表软组织感染患者随机被分为研究组(220例)和对照组(120例)。研究组给予病灶处芙蓉膏均匀外敷,每日更换1次,疗程1周。对照组给予病灶处金黄散均匀外敷,用法和疗程均同芙蓉膏。疗程结束后,记录患者局部肿块消散、红肿消退、疮口愈合和全身发热消退情况;分别评价两组总体疗效和单病种疗效;同时观察两组局部和全身毒性及不良反应。结果:两组疮口愈合、发热消退无显著性差异,但观察组对肿块消散、红肿消退有着更好的临床疗效,差异有显著性(P<0.01)。研究组总有效率优于对照组,差异具有显著性(P<0.01)。两组单病种疖和疽总有效率无显著性差异,但研究组单病种痈和丹毒总有效率优于对照组,差异有显著性(P<0.05,P<0.01)。两组局部毒性和不良反应均较低,差异无显著性(P>0.05)。两组均无明显的全身毒性和不良反应发生,两组毒性及不良反应比较,差异无显著性(P>0.05)。结论:芙蓉膏外敷治疗浅表软组织感染有着良好的临床疗效,无明显的局部和全身毒性及不良反应发生。Objective： To observe the clinical effect and toxicity of Furong ointment in treating superficial soft-tissue infection by external application. Methods： Three hundreds and forty cases of superficial soft tissue infection were randomly divided into study group （220 cases） and control group （120 cases）. The study group and control group were treated with Furong ointment and Jinhuang powder in the infected places externally and evenly, respectively, dressing changing daily and treatment course being one week. At the end of treatment course, the local mass dissipation, the inflamed retrogression, the opening sore healing and the fever retrogression were recorded. The overall effect and the single disease effect of the two groups were evaluated separately, and the local and systemic toxicity of the two groups were observed separately. Resuhs：The opening sore healing and the fever retrogression of the two groups had not significant difference, but local mass dissipation and the inflamed retrogression of the two groups had a better clinical curative effect,and the difference was significant （P〈0.01）. The total effective rate of the study group was better than that of the control group and the difference was significant （P〈0.01）. The totaleffective rates of furuncle and gangrene had no significant difference between two groups. But the total effec rive rates of carbuncle and erysipelas of the study group were significantly higher than those of the control group （P〈0.05,P〈0.01）. The local toxic-side reactions of two groups were low and the difference was not significant （P）0.05）. There were no significant systemic toxic-side reactions in the two groups （P〉 0.05）. Conclusion： Furong ointment has a fine clinical effect in treating the superficial soft-tissue infection by the external application without obvious local and systemic toxicity.

关 键 词：软组织感染 芙蓉膏 中医外治疗法 

分 类 号：R63[医药卫生—外科学]