蒙药塔本文都苏油丸对衰老小鼠皮层MDA、NO、SOD水平变化的影响  

EFFECTS OF MONGOLIAN MEDICINE TABEN WENDUSU OIL PILL ON MDA,NO AND SOD IN BRAIN OF AGED MICE

作　　者：曹瑞珍[1] 魏永春[1] 张国文[1] 佘集凯[1] 

机构地区：[1]内蒙古民族大学生命科学学院,通辽028041

出　　处：《现代预防医学》2009年第4期737-738,共2页Modern Preventive Medicine

摘　　要：[目的]探讨蒙药塔本文都苏(TBWDS)油丸抗衰老作用及其机制。[方法]采用半乳糖所致衰老小鼠连续给以塔本文都苏油丸灌胃40d后,测定小鼠脑组织中一氧化氮(NO)、丙二醛(MDA)和超氧化物歧化酶(SOD)水平。[结果]与模型组比较,塔本文都苏油丸可明显提高衰老模型小鼠脑组织中SOD的活性,降低脑组织中MDA和NO的含量。[结论]塔本文都苏油丸具有明显的抗衰老作用,此作用与其抗氧化损伤有关。[Objective] To investigate the effect and mechanism of Taben Wendusu （TBWDS） on anti-aging rats. [Methods]Aging rats induced by D-galaetose were treated with TBWDS for 40 days, and the contents of NO, MDA and SOD in the brain tissues were measured. [Results] When compared with model control group, TBWDS could decrease the contents of NO and MDA as well as increase the activity of SOD in the brain tissues of aging rats. [Conclusion] It is suggested that the TBWDS has an anti-aging effect, and the action mechanism showed association with its free radical scavenging activity.

关 键 词：塔本文都苏 D-半乳糖 NO MDA SOD 

分 类 号：R339.38[医药卫生—人体生理学]