预防性抗菌药物应用对乙型脑炎患儿预后的影响  

THE EFFECT OF PROPHYLACTIC ANTIBACTERIAL ON PROGNOSIS OF EPIDEMIC TYPE B ENCEPHALITIS

作　　者：钟利[1] 黄永茂[1] 邹永胜[1] 任小华[1] 刘泽明[1] 

机构地区：[1]泸州医学院附属医院感染科,四川泸州646000

出　　处：《泸州医学院学报》2009年第1期33-35,共3页Journal of Luzhou Medical College

摘　　要：目的:研究并确定抗菌药物的预防性应用对乙型脑炎患儿预后的影响。方法:72例乙型脑炎患者被随机分为治疗组和对照组,治疗组给予对症支持等常规治疗,而对照组除常规治疗外,给予抗菌药物预防可能发生的细菌感染,观察患儿预后、发热和意识障碍持续时间、发生感染的数量等有无差异。结果:治疗组和对照组在预后、发热和意识障碍持续时间,总的感染例次上没有显著性差异,而对照组发生真菌感染例次显著高于治疗组。结论:抗菌药物的应用不能改变乙型脑炎病人的预后、也不能减少细菌感染的发生率,还可能增加真菌感染的机会,在乙型脑炎的治疗中没有必要预防性应用抗菌药物。Objective：To study the effect of prophylactic antibacterial on prognosis of patients with epidemic type B encephalitis.Methods：72 cases were randomly divided into treatment group and control group. Treatment group received conventional treatment while control group received conventional treatment plus antibacterial treatment.The prognosis , the incidence of infection ,the duration of fever and unconsciousness were observed. Results：There were on significant differences in the prognosis, the incidence of infection and the duration of fever and unconsciousness betwere two groups,and the incidence of my cotic infection in control group was higher than in treatment group.Conclusion：Antibacterial can not alter the prognosis and decrease the incidence of infection in patients with epidemic type B encephalitis.We must not prophylactiely use antibacterial in treatment of epidemic type B encephalitis.

关 键 词：乙型脑炎 抗菌药物 预后 

分 类 号：R512.32[医药卫生—内科学]