格拉斯琼预防曲马多复合静脉麻醉术后镇痛恶心、呕吐的疗效观察  

THE PROPHYLACTIC EFFECT OF GRANISETRON ON POSTOPERATIVE NAUSEA AND VOMITING (PONV) DURING POSTOPERATIVE PCA WITH TRAMAL

作　　者：曹君[1] 朱翠容[1] 

机构地区：[1]泸州医学院附属医院手术室,四川泸州646000

出　　处：《泸州医学院学报》2009年第1期103-105,共3页Journal of Luzhou Medical College

摘　　要：目的:观察格拉斯琼对曲马多静脉复合麻醉术后镇痛(PCA)恶心、呕吐的预防作用。方法:将90例择期手术病人随机分为三组:对照组;氟哌利多组;格拉斯琼组。三组均采用曲马多静脉术后镇痛,所不同的是对照组镇痛配方中无格拉斯琼和氟哌利多,氟哌利多组镇痛配方中加入氟哌利多,格拉斯琼组镇痛配方中加入格拉斯琼,随访记录病人术后48小时内恶心呕吐的发生。结果:对照组恶心呕吐发生率明显高于格拉斯琼组和氟哌利多组;格拉斯琼对于预防术后恶心、呕吐的作用优于氟哌利多,氟哌利多组嗜睡的病例较格拉斯琼组和对照组明显增多。结论:格拉斯琼用于预防曲马多术后镇痛恶心、呕吐优于氟哌利多。Objective： To investigate the prophylactic effect of Granisetron on PONV during postoperative analgesia with Tramal. Method：90 patients were randomly devided into Droperidol group （n=30）, Granisetron group（n=30）,and Control group （n=30;without the use of Droperidol or Granisetron）.The patients were followed up and PONV recorded within 24h after procedures. Results： The incidenc of PONV in Control group was obviously higher than that in haloperidol group and Granisetron group,but the patients with drowsiness were much more in haloperidol group than in Granisetron group. Conclusion： Granisetron is better than haloperidol for preveniing PONV.beeause of much less drowsy cases.

关 键 词：格拉斯琼 曲马多 术后镇痛(PCA) 恶心 呕吐 

分 类 号：R614[医药卫生—麻醉学] R657.4[医药卫生—外科学]