肠道病毒71型感染18例临床分析  

Clinical analysis of 18 children with enterovirus 71 infection

作　　者：黄全发[1] 邓皓辉[1] 叶毅桦[1] 陈志凤[1] 曾伟斌[1] 张素芬[1] 李锐钦[1] 张若愚[1] 

机构地区：[1]东莞市人民医院儿科,523018

出　　处：《中国小儿急救医学》2009年第1期39-40,46,共3页Chinese Pediatric Emergency Medicine

摘　　要：目的探讨儿童肠道病毒71型（EV71）感染的临床特征。方法回顾性分析我院2008年4月至7月间18例EV71感染病例的流行病学特征及临床表现。结果发病年龄以3岁以下为主（89％），外地移居儿童发病率明显高于本地儿童。所有患儿均出现发热及皮疹（100％），合并肺炎5例（28％），肺水肿并肺出血2例（11％），心肌炎5例（28％），病毒性脑炎4例（22％）。治愈13例，好转2例，自动出院1例，死亡2例。结论重症病例主要由EV71感染引起；肢体抖动、膝反射亢进是重症病例较具特征的表现；白细胞增高、血糖升高对危重病例的早期发现有提示意义。Objective To study the clinical characteristics of enterovirus 71 infection in children. Methods A retrospective analysis was conducted to study the enterovirus 71 infection prevalence and clinical characteristics of our hospital during the period from April to July 2008. Results The onset age of most cases （89%） was below 3 years. Migrant children showed higher incidence than local children. All children had fever and skin rash （ 100% ） ,5 cases were combined with pneumonia （28%） ,2 cases with pulmonary e- dema and pulmonary hemorrhage （11%）,5 cases with myocarditis （28%）,4 cases with viral encephalitis （22%）. 13 cases were cured,2 cases showed improved signs and symptoms of enterovirus 71 infection, 1 case quitted and 2 cases died. Conclusion Severe cases are mainly caused by enterovirus 71. Jitter limbs and knee jerk hyperreflexia are characteristic in severe cases;higher WBC count and blood glucose rise are indicative for severe cases.

关 键 词：肠道病毒71型 手足口病 危重症 儿童 

分 类 号：R725.1[医药卫生—儿科]