响应表面优化法及其在天然产物成分提取中的应用  

Response Surface Method and Its Application in Natural Product Component Extraction

作　　者：王燕[1] 罗文谦[2] 张志琪[1] 

机构地区：[1]陕西师范大学化学与材料科学学院,陕西西安710062 [2]安康学院化学化工系,陕西安康725000

出　　处：《安康学院学报》2009年第1期77-81,共5页Journal of Ankang University

摘　　要：本文介绍一种广泛用于科学研究和生产实践中的实验条件多元优化方法——响应表面优化法(RSM),重点讨论其中应用最多的BBD法(Box-Behnken design),并通过详细论述应用BBD法优化微波辅助提取柿叶中总黄酮条件的过程,从实验设计、数据统计处理和分析对BBD法应用于天然产物成分提取进行系统的介绍.A method of optimization for the multi - variable experiment, response surface methodology, is intro-duced in this paper. It is focused on one of popular methodology of Box - Behnken design in RSM. The experiment condition for microwave - assisted extraction of total falconoid from Diospyros kaki leaves was optimized with BBD method. And the optimization procedure is discussed in order to systematically describe the application of BBD method to nature product component extraction.

关 键 词：响应表面法 BBD法 天然产物成分提取 微波提取 柿叶 总黄酮 

分 类 号：TQ041[化学工程]