附睾及附属性腺对精子运动能力的影响  

Effects of post testicular glands on sperm motility parameters

作　　者：高元奇[1] 郑贤红[1] 唐宇哲[1] 戴汝琳[1] 荣涛[1] 刘睿智[1] 

机构地区：[1]吉林大学白求恩医学院细胞生物学教研室(吉林省生殖医学研究所),吉林长春130021

出　　处：《中国现代医学杂志》2009年第2期296-299,共4页China Journal of Modern Medicine

基　　金：吉林省科技厅资助项目(No:200505140)

摘　　要：目的研究睾丸后附睾及附属性腺对精子运动能力的影响。方法630例精液样本采用计算机辅助精子分析(CASA)精子运动参数,把这些数值与精浆果糖、中性a-糖苷酶、前列腺特异性抗原及锌联系起来,并进行相关性分析。精浆果糖含量、中性a-糖苷酶、精浆锌采用分光光度比色法测定。PSA采用试剂盒进行检测。结果精液果糖含量异常组精子活力显著高于正常组(P<0.001),中性a-糖苷酶活性、精浆锌含量异常组精子活力均显著低于正常组(P<0.01,P<0.05)。精浆果糖含量与精子活力有明显的负相关性(r=-0.185,P<0.05),而精浆中性a-糖苷酶活性与精子活力有明显的正相关性(r=0.220,P<0.01)。结论附睾与附属性腺对精子运动能力有影响,其产生的生化标志物可能调节精子运动。[Objective] To study effect of post-testicular factors on sperm motility parameters. [Methods] Sperm samples were obtained from 630 patients of male infertility. Sperm motility was detected by eomputer assisted sperm analysis （CASA）. Seminal plasma fructose concentration, neutral a-glycosidase, zinc was measured by spectrophotometer. [Results] Sperm motility of abnormal seminal plasma neutral a-glyeosidase, zinc was significandy lower than that of normal group （P 〈0.001）. Sperm motility of abnormal seminal plasma fructose was significantly higher than that of normal group （P 〈0.01, P 〈0.05）. A significant negative correlation was observed between seminal plasma fructose and sperm motility （r =-0.185, P 〈0.05）. A significant positive correlation was observed between seminal plasma neutral a-glycosidase and sperm motility （r =0.220, P 〈0.01）.[Conclusion] Post-testieular glands influence sperm motility, and corresponding biochemistry marker can regulate sperm motility.

关 键 词：精子运动能力 附睾 附属性腺 果糖 中性a-糖苷酶 

分 类 号：R698.2[医药卫生—泌尿科学]