红厚壳叶中[口山]酮类成分  

Xanthones from leaves of Calophyllum inophyllum Linn.

作　　者：李媛[1] 李占林[1] 刘明生[2] 李丹毅[1] 张慧[1] 华会明[1] 

机构地区：[1]沈阳药科大学中药学院,辽宁沈阳110016 [2]海南医学院,海南海口571101

出　　处：《药学学报》2009年第2期154-157,共4页Acta Pharmaceutica Sinica

摘　　要：为了研究红厚壳叶中的(口山)酮类成分,采用多种色谱方法对红厚壳叶95%乙醇提取物进行分离纯化,从氯仿萃取物中分离得到1个新化合物inophyxanthone A(1)以及4个已知化合物pancixanthone A(2)、gerontoxanthone B(3)、jacareubin(4)和pyranojacareubin(5),其中化合物2为首次从该植物中分离得到,化合物3为首次从红厚壳属植物中分离得到。经波谱数据分析鉴定inophyxanthone A(1)的结构为1,3,5-三羟基-2-(1,1-二甲基-烯丙基)(口山)酮。To study the xanthones from the leaves of Calophyllum inophyllum Linn., several chromatography methods were employed to isolate the constituents. Investigation on the CHC13 extract led to the isolation of a new xanthone named inophyxanthone A （1） and four known compounds, which were pancixanthone A （2）, gerontoxanthone B （3）, jacareubin （4） and pyranojacareubin （5）. Among them, compound 2 was obtained from this plant firstly, and compound 3 was obtained for the first time from this genus. The structure of inophyxanthone A （1） was identified as 1, 3, 5-trihydroxy-2-（1, 1-dimethylallyl）xanthone by spectral analysis.

关 键 词：红厚壳 [口山]酮 inophyxanthone A 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]