妊娠合并多囊肾的母婴结局探讨  

Outcome of Pregnancy in Woman Complication with Polycystic Kidney Disease

作　　者：赵扬玉[1] 魏瑗[1] 张 王永清[1] 李诗兰[1] 叶蓉华[1] 王研[1] 乔杰[1] 

机构地区：[1]北京大学第三医院,北京100083

出　　处：《实用妇产科杂志》2009年第2期93-96,共4页Journal of Practical Obstetrics and Gynecology

摘　　要：目的:探讨妊娠合并多囊肾的诊断、治疗和预后。方法:对4例妊娠合并多囊肾患者的临床资料进行回顾性分析。结果:1例具有家族史的患者妊娠晚期伴发肾功能不全失代偿,孕37周分娩低出生体重儿,产后2年因肾功能衰竭行肾移植术;2例患者孕期证实多囊肾,孕晚期并发子痫前期及肾功能不全代偿,分别在孕39周及36周剖宫产分娩,母子平安出院;1例孕22周诊断多囊肾、肾功能不全失代偿行中期妊娠引产术。结论:患多囊肾孕妇多伴随肾功能不全,其母儿并发症明显增多。孕期加强监护,控制血压,保护肾功能可改善母儿预后,如出现肾功能衰竭时应及时终止妊娠。Objective： To investigate the diagnosis, treatment end prognosis of polycystic kidney disease （PKD） complication of pregnancy by 4 cases clinical review. Methods：Four gravidas with PKD were reported by retrospective review. Results：One case, with family history, was in the decompensation phase of renal failure in the third trimester. Low weight fetus was born in the 37th gestational week. Kidney transplantation was perforrried due to renal failure two years later. Two women were confirmed PKD during pregnancy, and suffered with severe preeciampsia end renal failure. Cesarean sections were performed respectively in the 39th and 36th gestational week. Both the mothers and the fetus were discharged restfully. Another gravida was diagnosed PKD end in the decompensation phase of renal failure in the 22th gestational week, then was performed artificial abortion. Conclusions; Gravidas with PKD have higher matemal and fetal complications than normal gravidas, and always accompany with renal failure. Enhancing monitor during pregnancy and effective controlling of blood pressure to protect renal function may be sufficient to improve pregnant outcome. The pregnancy should be terminated when renal failure occurs.

关 键 词：多囊肾 肾功能不全 妊娠 胎儿结局 

分 类 号：R714.258[医药卫生—妇产科学]