颅内感染患儿脑脊液中可溶性白细胞介素2受体的测定  

Measurement of Soluble Interleukin 2 Receptor in Cerebrospinal Fluid in Child Patients with Intracranial Infection

作　　者：朱长连[1] 冯红旗[1] 王小阳[1] 贾莉婷[1] 

机构地区：[1]河南医科大学第三附属医院,郑州450052

出　　处：《中国神经免疫学和神经病学杂志》1998年第1期36-38,共3页Chinese Journal of Neuroimmunology and Neurology

摘　　要：目的探讨脑脊液中可溶性白细胞介素2受体水平的变化对脑膜炎的鉴别诊断价值。方法用ELISA法对66例初诊为颅内感染患儿，其中化脓性脑膜炎（化脑）19例，结核性脑膜炎（结脑）20例，病毒性脑膜炎（病脑）27例．进行了脑脊液中可溶性白细胞介素2受体（sIL－2R）水平测定，并与对照组测定值进行比较。结果患儿组的测定位均明显高于对照组测定值．其中以结脑患儿组测定值最高，各患儿组之间的测定值均存在明显差别（P＜0．001）。结脑组和化脑组患儿sIL－2R的测定值存在部分重叠．与病脑组患儿的测定值无任何重叠。结论脑脊液中sIL－2R的测定可能有助于辅助病脑同结脑、化脑的鉴别。Objective To study differential diagnostic value of soluble interleukin 2 receptor (sIL2R) in cerebrospinal fluid (CSF) to the child patients with intracranial infection. MethodsThe sIL-2R in CSF was tested with ELISA method in 66 cases of child patient which werefirst admitted with intracranial infection (19 cases purulent meningitis, 20 cases tuberculousmeningitis and 27 cases viral meningitis) and 12 cases were served as control. Results Thelevel of sIL-2R in the patients group were auhigher than that of contro1 group. The level ofsIL-2R in the tuberculous rneningitis was the highest in all patient groups. There was someoverlaping of sIL-2R value between purulent meningitis group and tuberculos meningitis.Conclusion The determination of sIL-2R in CSF is probably an auxilliary method indifferential diagnosis of viral meningitis with tuberculous meningitis and purulentmeningit is.

关 键 词：脑脊液 脑膜炎 诊断 白细胞介素2 受体 小儿 

分 类 号：R725.123[医药卫生—儿科] R446.61[医药卫生—临床医学]