1%联苯苄唑乳膏治疗马拉色菌毛囊炎临床疗效观察  

Clinical effect of 1% bifonazole cream on Malassezia folliculitis

作　　者：潘永正[1] 王飞[1] 董正邦[1] 张敬东[1] 吴汉民[1] 

机构地区：[1]东南大学附属中大医院皮肤科,江苏南京210009

出　　处：《东南大学学报（医学版）》2009年第1期62-63,共2页Journal of Southeast University(Medical Science Edition)

摘　　要：目的:观察1%联苯苄唑乳膏治疗马拉色菌毛囊炎的临床疗效和安全性。方法:选择80例马拉色菌毛囊炎患者,治疗组(40例)外用1%联苯苄唑乳膏,每日1次,连续3周;对照组(40例)外用2%酮康唑洗剂。结果:3周疗程结束时治疗组临床整体疗效(用药后症状/体征积分下降指数)优于对照组(P<0.05),两组间真菌学清除率相当(P>0.05)。结论:1%联苯苄唑乳膏治疗马拉色菌毛囊炎疗效确切,安全性好。Objective To evaluate the clinical efficacy and safety of 1% bifonazole cream for the treatment of Malassezia folliculitis. Methods 80 patients of Malassezia foliculitis were divided into two groups. Treatment with 1% bifonazole cream or 2% ketoconazole lotion was applied once-daily to the affected area for 3 weeks. Efficacy assessment based on symptom/sign reducing index （SSRI）. Result The clinical efficacy of the treatment group was better than that of control （ P 〈 0. 05 ）. There was no significant difference in fungus clearance rate between the two groups. No systemic side effects were found. Conclusion Topical use of 1% bifonazole cream is safe and effective for the treatment of Malassezia folliculitis.

关 键 词：联苯苄唑 马拉色菌毛囊炎 

分 类 号：R756[医药卫生—皮肤病学与性病学]