5324例恶性肿瘤患者梅毒螺旋体抗体检测结果  

Testing Result of Treponema Pallidum Antibody in 5,324 Patients with Malignant Tumor

作　　者：宋燕[1] 于景云[1] 张凤华 

机构地区：[1]大连大学附属新华医院检验科,辽宁大连116021 [2]大连医科大学附属一院

出　　处：《实用预防医学》2009年第1期233-234,共2页Practical Preventive Medicine

摘　　要：目的探讨恶性肿瘤患者梅毒TP(Treponema Pallidum)感染的阳性分布趋势及其在不同肿瘤疾病中的分布情况。方法用ELISA法和TPPA法对在我院住院并确诊为恶性肿瘤的5 324例患者进行梅毒螺旋体抗体检测。结果恶性肿瘤患者梅毒螺旋体抗体阳性率为1.84%,明显高于一般人群。肿瘤患者男性感染率略高于女性,但无显著性差异。在51～70岁年龄段人数明显高于其他年龄段。不同恶性肿瘤患者TP感染的阳性率差异有统计学意义(P<0.01),以子宫内膜癌最高,其次是胰腺癌,卵巢癌等。结论恶性肿瘤患者梅毒感染的阳性率较高。建议恶性肿瘤患者住院应常规进行梅毒螺旋体检测,对预防医院感染,防止医疗纠纷具有重要意义。Objective To explore the positive distribution of Treponema pallidum antibody in patients with malignant tumor, and to analyze its distribution in different tumor diseases. Methods ELISA and TPPA were used to measure Treponema pallidum antibody in 5,324 inpatients with malignant tumor. Results The positive rate of Treponema pallidum antibody in patients with malignant tumor was 1. 84%, and it was significantly higher than that of normal subjects. The infection rate was higher in male tumor patients than female ones, but no significant difference was found between them. The infection rate was significantly higher in the age group of 51- 70 years. The positive rate of TP infection was significantly different in different malignant tumors （P〈 0.01）, endometrial carcinomas was the most common cancer, followed by pancreatic cancer, ovary cancer, etc. Conclusions The Positive rate of Treponema pallidum antibody in patients with malignant tumor is high. It is necessary to detect Treponema pallidum antibody in patients with malignant tumor, and it is of great value to prevention of nosocomial infection and medical dispute.

关 键 词：恶性肿瘤 梅毒 感染 

分 类 号：R377.1[医药卫生—病原生物学]