水杨酸乙酯体外抗菌活性的测定  

Determination of Ethyl Salicylate Anti-bacterial Activity in vitro

作　　者：陈晓玲[1] 裴海龙[1] 王希楠[1] 鲁海燕[1] 黄建新[1] 

机构地区：[1]西北大学生命科学学院,陕西西安710069

出　　处：《安徽农业科学》2009年第2期455-456,共2页Journal of Anhui Agricultural Sciences

基　　金：国家大学生创新实验计划基金[(国)200717(西北大学)]资助

摘　　要：[目的]测定水杨酸乙酯体外抗菌活性。[方法]采用琼脂稀释法进行水杨酸乙酯溶液体外抗菌活性的试验测定其最低抑菌浓度MIC值。[结果]测得水杨酸乙酯溶液体外对肠道常见细菌的MIC值为0．15～0．40mg／ml。其对各种菌都有较好的抑菌作用，对志贺氏菌属的抑制效果尤为明显。与复方乙酰水杨酸片相比，水杨酸乙酯抗菌作用强、抗菌谱广。[结论]水杨酸乙酯溶液对肠道常见细菌具有显著的抗菌作用。[ Objective ] To determine the minimum inhibitory concentrations of Ethyl salicylate anti-bacterial activity in vitro. [ Method ] Agardilution method was employed. [ Resuhs] The range of the MIC of Ethyl salicylate was from 0.15 mg/ml to 0.40 mg/ml, which had quite good inhibitory effect on all kinds of bacteria, esp. Shigella. Ethyl salicylate showed a better performance than compound aspirin tablet in anti-bacterial activities. [ Conclusion] The result showed Ethyl salicylate had obvious anti-bacterial activity.

关 键 词：水杨酸乙酯 格兰氏阳性菌 格兰氏阴性菌 最低抑菌浓度 琼脂稀释法 

分 类 号：O625.5[理学—有机化学]