乳香没药药对不同配比对无水乙醇致小鼠胃溃疡的保护作用  

Effect of different matching of Frankincense and Myrrh on resisting gastric ulcer in mice induced by absolute ethyl alcohol

作　　者：张朋[1] 马骏[1] 宋薇[1] 牛静[1] 王锋[1] 

机构地区：[1]甘肃中医学院,甘肃兰州730000

出　　处：《甘肃中医学院学报》2009年第1期12-13,共2页Journal of Gansu College of Traditional Chinese Medicine

基　　金：甘肃省中医药科研项目(编号:05-GZK-01)

摘　　要：目的观察乳香没药药对不同配比对无水乙醇致小鼠胃溃疡的保护作用。方法采用无水乙醇法复制小鼠胃溃疡模型,以溃疡指数为指标,评价乳香没药不同配比抗胃溃疡的作用。结果乳香组、乳香没药(3∶1)组、乳香没药(2∶2)组、乳香没药(1∶3)组和西咪替丁片组均能显著降低无水乙醇致胃溃疡模型的溃疡指数,提高溃疡抑制率,有高度统计意义,其中,乳香没药(2∶2)组作用最强。没药组溃疡指数有降低趋势,但无统计意义。结论乳香没药配伍抗无水乙醇致胃溃疡作用存在最佳配比。Objective To observe the effect of different matching of Frankincense and Myrrh on resisting gastric ulcer in mice induced by absolute ethyl alcohol. Methods Made gastric ulcer model of mice by absolute ethyl alcohol, and evaluated the effect of different matching of Frankincense and Myrrh on resisting gastric ulcer induced by absolute ethyl alcohol by ulcer index. Results Frankincense group, Frankincense and Myrrh （3： 1 ）group, Frankincense and Myrrh（2： 2） group, Frankincense and Myrrh（ 1：3 ） group and Cimetidine Tablet group could prominently reduce ulcer index of gastric ulcer model induced by absolute ethyl alco- hol, and increase the inhibitory rate of ulcer, there was very significant difference, and the effect of Frankin- cense and Myrrh（2： 2） group was strongest. Myrrh group had the trend of lower, but there was no significant difference. Conclusion There is the best ratio different matching of and Frankincense Myrrh resisting gastric ulcer in mice induced by absolute ethyl alcohol.

关 键 词：乳香 没药 无水乙醇 胃溃疡 

分 类 号：R285.5[医药卫生—中药学]