希夫碱型大环多胺锌配合物对α-吡啶甲酸对硝基苯酚酯催化水解的研究  

Kinetic investigation on hydrolysis of p-nitrophenyl picolinate catalyzed by zinc complex of Schiff base macrocyclic polyamine

作　　者：刘凡[1] 唐典勇[1] 刘志昌[1] 张元勤[1] 

机构地区：[1]乐山师范学院化学与生命科学学院,四川乐山614004

出　　处：《化学研究与应用》2009年第2期248-253,共6页Chemical Research and Application

基　　金：四川省教育厅资助项目(08ZC038)

摘　　要：The kinetics of the hydrolysis of p-nitrophenyl picolinate(PNPP) catalyzed by zinc complex of schiff base macrocyclic polyamine(Zn2+ complex of 1,4,7,10,13,16-hexaazacyclooctadeca-1,3,10,12-tetraene was abbreviated to ZnL2+)were studied at 25℃and pH=7.00.The pseudo-first-order rate constant(kψ)of the catalytic PNPP hydrolysis was 8.85×10-3 s-1,which was 463 times larger than that of the spontaneous hydrolysis of PNPP at pH=7.00.The effect of surfactants(Brij35,CTAB,and SDS),pH,temperature,and the concentration of ZnL2+ on the PNPP hydrolysis catalyzed by ZnL2+ was also studied in present paper.The thermodynamic and kinetic parameters of the titled reaction were obtained with the mathematical model.The activated water molecule in the reactant-catalyst complex was a strongly nucleophilic species,which could promote the PNNP hydrolysis reaction effectively.The kinetics of the hydrolysis of p-nitrophenyl picohnate （PNPP） catalyzed by zinc complex of schiff base macrocyclic polyamine （ Zn^2＋ complex of 1,4,7, 10,13,16 -hexaazacyclooctadeca- 1,3,10,12-tetraene was abbreviated to ZnL^2＋） were studied at 25℃ and pH = 7.00. The pseudo-first-order rate constant （ kψ） of the catalytic PNPP hydrolysis was 8.85 × 10^-3 s^-1 , which was 463 times larger than that of the spontaneous hydrolysis of PNPP at pH =7.00. The effect of surfactants （Brij35 ,CTAB,and SDS） ,pH,temperature,and the concentration of ZnL^2＋ on the PNPP hydrolysis catalyzed by ZnL^2＋ was also studied in present paper. The thermodynamic and kinetic parameters of the titled reaction were obtained with the mathematical model. The activated water molecule in the reactant-catalyst complex was a strongly nucleophilic species, which could promote the PNNP hydrolysis reaction effectively.

关 键 词：希夫碱型大环多胺 锌(Ⅱ)配合物 PNPP 催化水解 

分 类 号：O643.12[理学—物理化学]