地方性氟中毒病区胎儿肾上腺皮质细胞超微结构体视学研究  

Stereological study on adrenal gland cortex of human fetuses from a fluorosis endemia

作　　者：于燕妮[1] 刘家骝[1] 董仲[1] 

机构地区：[1]贵阳医学院病理教研室

出　　处：《中国地方病学杂志》1998年第1期41-43,共3页Chinese Jouranl of Endemiology

摘　　要：对地方性氟病病区胎儿肾上腺皮质细胞进行超微结构体视学研究。结果显示：病区胎儿肾上腺皮质细胞核比表面和核平均体积缩小，细胞平均截面积和平均体积缩小；线粒体肿胀，平均周长和平均体积增大；粗面内质网体密度缩小。结果表明：机体过量氟对胎儿肾上腺皮质细胞超微结构有损伤作用。The adrenal gland cortexes of human fetuses from an endemicfluorosis region were studied with stereological method.The results showed that as compared with those of the fetuses from a nonendemicfluorosis region,the following indicators were reduced:(1)the nuclear specific surface and the average volume of the cortex cells;(2) the average intersurface and the average volume of the cortex cells;But the average perimeter and the average volume of the mitochondria were increased;(3) the volume density of the rough endoplasmic reticula.The results suggest that the excessive deposition of fluoride may damage the cellular organs of the cortex.

关 键 词：氟中毒 胎儿 肾上腺 体视学 地方病 超微结构 

分 类 号：R595.9[医药卫生—内科学] R329.456[医药卫生—临床医学]