基于图形表达的基因序列模糊聚类应用研究  

Application Research of Fuzzy Clustering Analysis Based on Graphical Representation of DNA Sequences

作　　者：周迎春[1] 骆嘉伟[2] 

机构地区：[1]湛江师范学院信息科学与技术学院,广东湛江524048 [2]湖南大学计算机与通信学院,湖南长沙410082

出　　处：《武汉理工大学学报（信息与管理工程版）》2009年第1期25-29,共5页Journal of Wuhan University of Technology：Information & Management Engineering

基　　金：湖南省自然科学重点基金资助项目(06JJ4076);湖南省财政厅基金资助项目(200590)

摘　　要：给出了一种新的非退化的基因图形三维表达方法,这一表达方法不仅避免了图形的重叠和交叉,同时还保留了序列的生物学特征。利用这种表达方法对H5N1病毒基因序列进行数字特征的提取,并引入基于多维PFS判别函数进行模糊聚类分析应用。在聚类分析过程中直接利用数字特征作为源数据,分析结果表明,利用该图形表达建立基因序列数字特征矩阵进行的聚类分析具有一定的合理性。A novel 3 - D graphic representation with nondegeneration was presented. This representation has the virtue of avoiding the overlap or cross without losing biological information. The proposed method was used to abstract the numeral character of HSN1 virus gene sequence. A clustering analysis based on the multi - dimension PFS parameter was proposed. In the procedure of clustering,the character was used as the data source. The result shows that it is rational to make clustering analysis on the gene character abstract from the new graphic representation.

关 键 词：基因图形表达 聚类分析 伪F统计量 

分 类 号：TP39[自动化与计算机技术—计算机应用技术]