DNA-蛋白质相互作用研究的方法及其新进展  

Advances in the Techniques for Studying the DNA-protein Interactions

作　　者：蔡容华[1] 李强[1] 张建军[1] 邢佩佩[1] 施碧红[1] 

机构地区：[1]福建师范大学教育部工业微生物工程研究中心,福建师范大学生命科学学院,福建福州350108

出　　处：《生物技术》2009年第1期93-97,F0004,共6页Biotechnology

基　　金：福建省自然科学基金项目资助(No.B0610027)

摘　　要：DNA与蛋白质的相互作用参与生命体内的许多生物学过程,关于二者相互作用的研究是人们了解基因表达机制、揭开生命奥秘的关键所在。该文简要阐述了传统研究DNA-蛋白质相互作用的常用方法及其优缺点,并综述了近年来该领域所采用的新技术及其新进展。Protein- DNA interactions participate in many biological processes. It plays a key role in knowing the truth of genome regulation and unravelling the mysteries of life. In the present paper, the classical methods and their advantages and disadvantages for investigation the interactions of DNA - protein have been reviewed. Meanwhile, the latest advances in the new techniques for studying protein - DNA interactions were described, and the perspectives on the future development were also propesed.

关 键 词：相互作用 DNA 蛋白质 研究技术 

分 类 号：Q81[生物学—生物工程]