RNA干扰与肿瘤基因治疗  

RNA Interference and Tumor Gene Therapy

作　　者：鞠吉雨[1] 李在连[1] 

机构地区：[1]潍坊医学院免疫学教研室山东省高校免疫学重点实验室,山东潍坊261042

出　　处：《食品与药品》2009年第1期54-57,共4页Food and Drug

摘　　要：RNA干扰(RNAi)是控制正常基因表达的一种机制,近来作为一种潜在的技术用于肿瘤、传染病和代谢性疾病的治疗。本文仅就RNA干扰的发现、作用机制以及在肿瘤治疗中的应用和所面临的问题做一简要介绍。RNA interference is a mechanism for controlling normal gene expression, which has been employed as a potential technology for a wide range of disorders such as tumors, infectious diseases and metabolic disorders. This paper reviews the discovery, mechanism of RNA interference and its application in tumor diagnosis and prevention, as well as some challenges.

关 键 词：RNA干扰 小干扰RNA 基因沉默 肿瘤 

分 类 号：Q522[生物学—生物化学]