血清胱抑素C—评价肾功能的新指标  

Serum Cystatin C-A New Marker for the Evaluation Kidney Function

作　　者：段晓星[1] 张国光[1] 梦雅平[1] 

机构地区：[1]内蒙古医学院附属医院肾脏内科,内蒙古呼和浩特010050

出　　处：《内蒙古医学杂志》2009年第1期73-76,共4页Inner Mongolia Medical Journal

摘　　要：临床上常用的评价肾小球滤过功能的指标如血清尿素氮(BUN)、血清肌酐(Scr)、内生肌酐清除率(Ccr)等都存在一定的局限性,并且不同程度受到一些其它因素的影响。血清胱抑素C(Cystatin C)是近年来报道的反映肾小球滤过率(GFR)的内源性新指标。与Scr和Ccr相比,Cystatin C可以更为准确、可靠的反映GFR,对早期诊断各种急慢性肾脏病患者具有重要价值。The indexs such as Blood urea nitrogen（BUN）, Serum creatinine（Scr）, Creatinine clearance rate （Ccr）, which are usually used to evaluate the function of glomerular filtration have somewhat limitations, what is more, they are often affected by other factors. Cystatin C is an ideal endogenic index reported recently to deter- mine glomerular filtration rate（GFR）. Serum Cystatin C determination is an accurate and reliable parameter of GFR. It can be a better marker for detection of early renal disfunction in patients with acute or chronic kidney disease than Scr and Ccr.

关 键 词：血清胱抑素C 肾小球滤过率 肾脏病 

分 类 号：R334.1[医药卫生—人体生理学]