人类白细胞抗原-G及其与妇科肿瘤的关系  

Correlation between human leukocyte antigen G and gynecological neoplasms

作　　者：韩雪川(综述)[1] 赵兴波(审校)[1] 

机构地区：[1]山东大学附属省立医院妇产科,济南250021

出　　处：《国际肿瘤学杂志》2009年第2期144-146,共3页Journal of International Oncology

摘　　要：免疫逃逸在妇科恶性肿瘤发病中的作用日益受到重视。人类白细胞抗原-G（HLA—G）分子是主要组织相容复合物Ⅰ家族中的主要成员，具有抑制免疫的作用，在妇科肿瘤的免疫逃逸中发挥了重要作用。The immune tolerance or immune escape plays important roles in the genesis and progression of malignant gynecological neoplasms, Human leukocyte antigen G （ HLA- G） is an important member of major histocompatiblity complex class Ⅰ . HLA-G seems to affect almost every aspect of human immunity. It can inhibit immunological function, and play an important role in immune escape of malignant gynecological neoplasms.

关 键 词：HLA抗原 组织相容性抗原Ⅰ类 免疫耐受 生殖器肿瘤 女(雌)性 

分 类 号：R392.11[医药卫生—免疫学] R737.3[医药卫生—基础医学]