六味地黄丸系列中成药快检方法研究  

Study on screening test of Liuwei Dihuang pills series

作　　者：薛玉梅[1] 黄丽丹[1] 王鼎[1] 

机构地区：[1]安徽省食品药品检验所,合肥230051

出　　处：《药物分析杂志》2009年第2期282-284,共3页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:建立用于药品检测车上快速筛检六味地黄丸系列中成药的快检方法。方法:采用乙醇研磨制备供试品溶液,分别用环己烷-乙酸乙酯(3∶1)、乙酸乙酯-无水乙醇-冰醋酸(50∶10∶1)为展开剂,对丹皮酚、熊果酸和马钱苷进行薄层色谱定性鉴别。结果:丹皮酚、熊果酸和马钱苷均可用TLC迅速检出。结论:所建立的方法快速、简便,可用于药品检测车上该类制剂的快速筛检。Objective：To establish the methods for screening the Liuwei Dihuang pills series in the drug testing ve- hicles. Methods：Sample was triturated with ethanol and plates were used with cyelohexane - ethyl acetate （3：1 ）, ethyl acetate- ethanol absolute -acetic acid glacial （50： 10：1 ） as developing solvent for identify paeonol .ursolie acid and loganin by TLC. Results：Paeonol, ursolie acid and loganin could be identified quickly by TLC. Conclusion： The methods are simple, fast, accurate and can be used for the screening test of Liuwei Dihuang pills series in the drug testing vehicles.

关 键 词：六味地黄丸系列 快检方法 薄层色谱 

分 类 号：R917[医药卫生—药物分析学]