易制毒化学品快速检测新技术  

Real-time Measurements of the Drug Precursor Chemicals with Proton Transfer Reaction Mass Spectrometry

作　　者：沈成银[1,2] 李建权 王鸿梅[1,2] 韩海燕 徐国华 郑培超[1,2] 王玉杰 李虎 储焰南 

机构地区：[1]中科院安徽光学精密机械研究所环境光谱学实验室 [2]中科院环境光学与技术重点实验室,安徽合肥230031

出　　处：《湖南大学学报（自然科学版）》2009年第2期75-79,共5页Journal of Hunan University:Natural Sciences

基　　金：国家自然科学基金资助项目(20577049;20707025);中国科学院仪器研制资助项目(Y2005015);安徽省'十一五'科技攻关项目(06012085B);安徽省优秀青年科技基金项目(06045098)

摘　　要：在自行研制的质子转移反应质谱(Proton Transfer Reaction Mass Spectrometry,PTR-MS)装置上以丁酮、乙醚等几种常见易制毒化学品为例给出检测结果.发现各自对应唯一的质子化离子峰,谱峰识别简单;分析其他易制毒化学品质子亲和势,说明PTR-MS可以对大部分易制毒化学品检测;对浓度为54±3 nmol/L的甲苯标准气体检测结果为51±0.5 nmol/L,绝对量检测准确;通过分析经铂丝催化后的本底信号得到PTR-MS对易制毒化学品的检测限,其中对甲苯检测下限可达5.0×10-2(±50%)nmol/L.结果表明,PTR-MS可选择合适的漂移管约化场E/N,实现对痕量易制毒化学品快速筛选和准确识别.Rapid detection of drug precursor chemicals is very important in the control of the lawless synthesis and bargaining for drug. In this paper, our homemade Proton Transfer Reaction Mass Spectrometry （PTRMS） was introduced and applied to the detection of drug precursor chemicals. Their mass spectra, such as 2-bu- tanone and ethyl ether, were given. The single protonated ion spectrum was obtained for them. The proton affinities of the drug precursor chemicals listed in the article has proved that most chemicals can be measured with PTR-MS. The measurement result from PTR-MS is fit to the concentration of standard gas of toluene. The limit of detections （LODs） for the drug precursor chemicals was analyzed through the background signals, which were determined with the catalytic converter. Toluene can be detected at a concentration of 5.0 × 10^-2 （ ± 50% ） nmol/L for the vapor. PTR-MS can be applied to scan the suspected drug precursor chemicals rapidly and to identify them exactly bv changing the reduced field across the drift tube.

关 键 词：质子转移反应质谱 易制毒化学品 实时 化学电离 

分 类 号：O657[理学—分析化学]