胺碘酮治疗急性心肌梗死室性心律失常180例临床报告  

Clinical report of amiodarone on the treatment of ventricular arrhythmia in 180 patients with acute myocardial infarction

作　　者：蔡飞[1] 李刚[1] 吴立群[2] 顾刚[2] 胡文英[2] 

机构地区：[1]南通市第三人民医院心内科,江苏南通226006 [2]上海交通大学附属瑞金医院,上海200020

出　　处：《江苏大学学报（医学版）》2009年第1期74-75,77,共3页Journal of Jiangsu University：Medicine Edition

摘　　要：目的：评价胺碘酮治疗急性心肌梗死（acute myocardial infarction，AMI）室性心律失常的疗效和安全性。方法：观察180例AMI患者采用胺碘酮治疗室性心律失常的疗效和安全性，随访1年。结果：反复发作的持续性室速、室颤患者，首剂3-5 mg/kg胺碘酮10 min内静脉注射；再以1-1.5 mg/min维持，室速均被有效终止。以200 mg/d胺碘酮作为长期维持量能有效控制室性期前收缩。结论：采用胺碘酮治疗AMI患者室性心律失常效果满意，安全可靠。Objective： To evaluate the efficacy and safety of amiodarone in the treatment of ventricular arrhythmia in patients with acute myocardial infarction.Methods： One hundred and eighty patients with ventricular arrhythmia and acute myocardial infarction were treated with amiodarone and followed up one year. Results： Intravenous loading dose of 3-5 mg/kg amiodarone was given within 10 minutes,followed by 1-1.5 mg/min infusion.The administration of amiodarone was effective in patients with recurrent sustained ventricular tachycardia and（or） fibrillation.Oral maintenance amiodarone dose of 200 mg/d could control ventricular arrythmia. Conclusion： Amiodarone had high efficacy and was relatively safe for treating ventricular arrhythmia in patient with acute myocardial infarction.

关 键 词：胺碘酮 急性心肌梗死 室性心律失常 随访 

分 类 号：R542.2[医药卫生—心血管疾病]