亮氨酸及其代谢产物促进蛋白质合成的分子机制及其补充效果  

Molecular mechanisms of leucine and its metabolite in improving protein synthesis and the effects of supplementation

作　　者：张庆[1] 漆正堂[1] 丁树哲[1] 

机构地区：[1]华东师范大学体育与健康学院,上海200241

出　　处：《生命的化学》2009年第1期103-107,共5页Chemistry of Life

基　　金：上海市浦江人才计划项目(4038470)资助

摘　　要：亮氨酸是人体必需的支链氨基酸,亮氨酸及其代谢产物对于蛋白质的代谢调节、骨骼肌的葡萄糖摄取有重要作用。但是亮氨酸调节作用的分子机制至今尚未完全阐明,不同项目、不同运动员个体的补充方式、补充剂量等方面的研究结果也不一致。本文对亮氨酸及其代谢产物在运动中对蛋白质合成、骨骼肌葡萄糖摄取的作用、分子机制,以及补充亮氨酸的研究现状加以综述。In human body, leucine is the essential branched chain amino acid. Leucine and its metabolites play an important role in regulating the protein metabolism and the uptake of glucose. The molecular mechanisms of regulation of leucine have not yet been fully explained. There are also different results in the supplement methods, supplement dosage during varieties of sports. This paper reviewed the leucine＇s influence on the synthesis of protein, glucose uptake, molecular mechanism and current research progress of leucine supplement.

关 键 词：亮氨酸 蛋白质代谢 骨骼肌 葡萄糖摄取 

分 类 号：Q591.2[生物学—生物化学]